SCHEMBL2270880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2276177	0.85	SLC16A3 (0.55)	GAAHPGDALDH1A1KDM4EKCNMA1
	SCHEMBL2276434	0.85	RAB9A (0.55)	NPC1GAAALDH1A1MEN1KMT2A
	SCHEMBL2275852	0.85	MEN1 (0.55)	ALOX15LMNANPC1HPGDALDH1A1
	SCHEMBL2275929	0.85	KMT2A (0.62)	MAPTMEN1KMT2ATDP1PLK1
	SCHEMBL2270925	0.83	PLK1 (0.57)	HTTALDH1A1MAPTMEN1KMT2A
	SCHEMBL2274245	0.82	LMNA (0.49)	HTTLMNANPC1TP53HSD17B10
	SCHEMBL2276347	0.82	MEN1 (0.56)	LMNAGAAMEN1KMT2ARECQL
	SCHEMBL6093021	0.81	LMNA (0.60)	HTTLMNANPC1TP53GAA
	SCHEMBL2278451	0.81	LTC4S (0.60)	ALDH1A1MAPTMEN1KMT2AHCAR2
	SCHEMBL4215640	0.81	MEN1 (0.52)	MEN1KMT2AHCAR2RECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.