SCHEMBL2276321

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2275722	0.90	ACLY (0.57)	ACLYSUCNR1NPC1RAB9A
	SCHEMBL14429486	0.86	KCNMA1 (0.44)	ACLYPTGER4PTGER2SUCNR1KCNMA1
	SCHEMBL2278464	0.85	ACLY (0.49)	ACLYSUCNR1HCAR2NPC1RAB9A
	SCHEMBL2269657	0.85	ALDH1A1 (0.45)	ACLYPTGER4PTGER2KCNMA1NPC1
	SCHEMBL27696863	0.83	ACLY (0.62)	ACLYSUCNR1HCAR2GRIK1SERPINE1
	SCHEMBL2276482	0.81	ACLY (0.74)	ACLYSUCNR1GRIK1SERPINE1NPC1
	SCHEMBL2268189	0.81	ACLY (0.61)	ACLYSUCNR1NPC1RAB9A
	SCHEMBL2274223	0.80	ALDH1A1 (0.53)	GRIK1NPC1RAB9A
	SCHEMBL12117713	0.80	ALDH1A1 (0.50)	ACLYNPC1RAB9A
	SCHEMBL4209151	0.79	ACLY (0.55)	ACLYSUCNR1HCAR2GRIK1DCLRE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.