Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MPI | P34949 | 2/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864155 | 0.84 | SLC40A1 (0.43) | HTR5AKDM4EL3MBTL1SLC40A1KMT2A | |
| SCHEMBL22864232 | 0.77 | HDAC6 (0.46) | HTR5AKDM4EL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL22864147 | 0.76 | PSMD14 (0.46) | KDM4EL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL13462244 | 0.76 | KDM4E (0.56) | HTR5AKDM4EL3MBTL1MPISLC40A1 | |
| SCHEMBL22864222 | 0.75 | ALDH1A1 (0.34) | KDM4EKMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL22864229 | 0.75 | CCR1 (0.41) | KDM4EL3MBTL1SLC40A1KMT2ALMNA | |
| SCHEMBL22864224 | 0.75 | SLC40A1 (0.39) | KDM4EL3MBTL1SLC40A1KMT2ANPC1 | |
| SCHEMBL2563593 | 0.72 | KDM4E (0.56) | HTR5AKDM4EL3MBTL1MPISLC40A1 | |
| SCHEMBL24631015 | 0.72 | HIF1A (0.46) | HTR5AKDM4EL3MBTL1MPISLC40A1 | |
| SCHEMBL22493402 | 0.71 | P2RX7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315534-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. | 2022-10-06 | — | — | US | disclosed |
| WO-2021003161-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315534-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | ADRB2, ADRB1, ADRA2C | HTR5A 120/4885KDM4E 4707/4885L3MBTL1 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.