Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30282920 | 0.89 | LMNA (0.45) | SIGMAR1HTR3AL3MBTL1HTR3EHTR3B | |
| SCHEMBL6672052 | 0.84 | ADRB1 (0.54) | HTR3AADRB1HTR2CHTR6HTR1A | |
| SCHEMBL6283138 | 0.79 | MEN1 (0.46) | ADRB1LMNAUSP2HTR6HTR1A | |
| SCHEMBL6668632 | 0.79 | HDAC4 (0.40) | ADRB1HTR2CLMNAHRH4HTR6 | |
| SCHEMBL22581853 | 0.75 | HTR3E (0.61) | SIGMAR1HTR3AHTR3EHTR3BADRB1 | |
| SCHEMBL27460680 | 0.75 | L3MBTL1 (0.43) | L3MBTL1LMNAPKMNPSR1USP2 | |
| SCHEMBL15554627 | 0.74 | ALK (0.65) | — | |
| Phenylpiperazine SCHEMBL10745401 | 0.73 | SIGMAR1 (0.79) | SIGMAR1HTR3AHTR3EHTR3BADRB1 | |
| SCHEMBL27677663 | 0.73 | SIGMAR1 (0.53) | SIGMAR1HTR3AHTR3EHTR3BADRB1 | |
| SCHEMBL5573099 | 0.72 | DRD4 (0.74) | SIGMAR1HTR3AL3MBTL1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| CN-110198938-B | Bis-heteroaryl derivatives as modulators of protein aggregation | UCB生物制药私人有限公司 | 2023-03-14 | — | — | CN | disclosed |
| US-10913735-B2 | Bis-heteroaryl derivatives as modulators of protein aggregation | UCB Biopharma SRL (BE) | 2021-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913735-B2 | Bis-heteroaryl derivatives as modulators of protein aggregation | PARK7, HTT, SNCA | SIGMAR1 4007/4885HTR3A 931/4885L3MBTL1 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.