Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628649 | 1.00 | TRPM8 (0.77) | TRPM8TP53POLBTSHRKMT2A | |
| Acoltremon SCHEMBL619824 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL2575067 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL29570327 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL23870506 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL23198293 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL3228667 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL17104729 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL14811473 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 | |
| Acoltremon SCHEMBL16227989 | 0.87 | TRPM8 (1.00) | TRPM8POLBKMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533760-A1 | LIQUID COMPOSITION COMPRISING A NON-MENTHOL COOLING AGENT AND A THICKENER FOR TREATING A RESPIRATORY SYMPTOM | The Procter & Gamble Company (US) | 2012-12-19 | — | — | EP | claimed |
| WO-2011100267-A1 | LIQUID COMPOSITION COMPRISING A NON-MENTHOL COOLING AGENT AND A THICKENER FOR TREATING A RESPIRATORY SYMPTOM | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-18 | — | — | WO | claimed |
| US-20110195042-A1 | Compositions, Methods and Kits Useful for Treating a Respiratory Symptom | THE PROCTER & GAMBLE COMPANY | 2011-08-11 | — | — | US | claimed |
| US-12521320-B2 | Oral care compositions comprising fluoride ions | THE PROCTER & GAMBLE COMPANY (US) | 2026-01-13 | — | — | US | disclosed |
| CN-119095581-A | Unit dose oral care compositions comprising fluoride | 宝洁公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-113365598-B | Container for personal health compositions | 宝洁公司 | 2024-08-30 | — | — | CN | disclosed |
| US-20240225968-A1 | Oral Care Compositions Comprising Metal Ions | PROCTER & GAMBLE (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240209375-A1 | Aptamers For Personal Health Care Applications | PROCTER & GAMBLE (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240197578-A1 | Foaming Oral Care Compositions | PROCTER & GAMBLE (US) | 2024-06-20 | — | — | US | disclosed |
| US-11964059-B2 | Methods of delivering an oral care active by administering oral care articles comprising a filament | THE PROCTER & GAMBLE COMPANY (US) | 2024-04-23 | — | — | US | disclosed |
| US-11944694-B2 | Foaming oral care compositions | THE PROCTER & GAMBLE COMPANY (US) | 2024-04-02 | — | — | US | disclosed |
| WO-2012003350-A1 | METHODS OF DELIVERING A HEALTH CARE ACTIVE BY ADMINISTERING PERSONAL HEALTH CARE ARTICLES COMPRISING A FILAMENT | THE PROCTER & GAMBLE COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012003365-A1 | FILAMENTS COMPRISING AN INGESTIBLE ACTIVE AGENT NONWOVEN WEBS AND METHODS FOR MAKING SAME | THE PROCTER & GAMBLE COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011100267-A1 | LIQUID COMPOSITION COMPRISING A NON-MENTHOL COOLING AGENT AND A THICKENER FOR TREATING A RESPIRATORY SYMPTOM | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-18 | — | — | WO | disclosed |
| US-20110195042-A1 | Compositions, Methods and Kits Useful for Treating a Respiratory Symptom | THE PROCTER & GAMBLE COMPANY | 2011-08-11 | — | — | US | disclosed |
| EP-2219677-A1 | PREPARATIONS, METHODS AND KITS USEFUL FOR TREATMENT OF COUGH | The Procter & Gamble Company (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2217279-A2 | PREPARATIONS, METHODS AND KITS USEFUL FOR TREATMENT OF COUGH | The Procter & Gamble Company (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009066262-A1 | PREPARATIONS, METHODS AND KITS USEFUL FOR TREATMENT OF COUGH | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009067605-A2 | PREPARATIONS, METHODS AND KITS USEFUL FOR TREATMENT OF COUGH | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-28 | — | — | WO | disclosed |
| US-20090130199-A1 | Preparations, Methods And Kits Useful For The Treatment of Cough | THE PROCTER & GAMBLE COMPANY (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195042-A1 | Compositions, Methods and Kits Useful for Treating a Respiratory Symptom | MUC1, TAS2R42, TAS2R7 | TRPM8 34/4885TP53 1874/4885POLB 818/4885 |
| US-11964059-B2 | Methods of delivering an oral care active by administering oral care articles comprising a filament | SMCHD1, ACTN1, KRT18 | TRPM8 4274/4885TP53 3484/4885POLB 656/4885 |
| US-20240197578-A1 | Foaming Oral Care Compositions | FOS, STOM, UGCG | TRPM8 3696/4885TP53 1932/4885POLB 1759/4885 |
| US-20090130199-A1 | Preparations, Methods And Kits Useful For The Treatment of Cough | CCL11, HRH2, CRH | TRPM8 563/4885TP53 4862/4885POLB 2373/4885 |
| US-20240225968-A1 | Oral Care Compositions Comprising Metal Ions | SLC39A7, SLC30A7, SLC39A3 | TRPM8 418/4885TP53 1880/4885POLB 1364/4885 |
| US-11944694-B2 | Foaming oral care compositions | FOS, STOM, UGCG | TRPM8 3696/4885TP53 1932/4885POLB 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.