SCHEMBL22972964

SCHEMBL22972964

C[Si]1(C)c2cc(O)ccc2Nc2ccc(O)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
PDPK1 O15530 4/20 0.33
TYR P14679 3/20 0.33
GAA P10253 2/20 0.33
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33
RAD51 Q06609 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16865798 0.70 DRD1 (0.46) DRD2DRD4
SCHEMBL15362327 0.68 ESR2 (0.56) MAOAMAOBCA1CA2CA7
SCHEMBL14508362 0.67 DRD2 (0.46) DRD2DRD4MAOAMAOBTYR
SCHEMBL25646431 0.65 RORC (0.49) MAOBUSP2ALDH1A1HPGD
SCHEMBL23767923 0.65 CA12 (0.50) DRD2DRD4MAOAMAOBCA12
SCHEMBL29720610 0.64 ALOX5 (0.46) DRD2DRD4MAOAMAOBCA12
SCHEMBL6045738 0.64 ALOX5 (0.46) DRD2DRD4MAOAMAOBCA12
SCHEMBL8941074 0.64 MAOA (0.55) DRD2DRD4MAOAMAOBCA12
SCHEMBL23434692 0.64 GNG2 (0.35) GAAALDH1A1
SCHEMBL23295852 0.60 NOX1 (0.43) GAAMEN1MAPTKMT2AEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3774821-B1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIV (TR) 2025-04-30 EP disclosed
US-20240342286-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2024-10-17 US disclosed
EP-4001285-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2022-05-25 EP disclosed
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-08-19 US disclosed
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-08-19 US disclosed
EP-3774821-A2 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS PPIF, MT-ND2, PPOX DRD2 4109/4885DRD4 4062/4885MAOA 2207/4885
US-20240342286-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS PPIF, MT-ND2, PPOX DRD2 4109/4885DRD4 4062/4885MAOA 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.