Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.46 |
| ▸ | DRD2 | P14416 | 11/20 | 0.46 |
| ▸ | DRD5 | P21918 | 10/20 | 0.46 |
| ▸ | DRD3 | P35462 | 9/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 7/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26730321 | 0.79 | DRD1 (0.40) | DRD1DRD2DRD5DRD3HSD17B1 | |
| SCHEMBL30005495 | 0.74 | AHR (0.37) | DRD2DRD4 | |
| SCHEMBL16263281 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL14317167 | 0.71 | DRD1 (0.61) | DRD1DRD2DRD5DRD3HSD17B1 | |
| SCHEMBL30672580 | 0.71 | — | — | |
| SCHEMBL21318766 | 0.71 | — | — | |
| SCHEMBL22972964 | 0.70 | DRD2 (0.35) | DRD2DRD4 | |
| SCHEMBL16736957 | 0.69 | PBRM1 (0.52) | DRD1DRD2DRD5DRD3HSD17B1 | |
| SCHEMBL788852 | 0.69 | HSD17B1 (0.64) | DRD1DRD2DRD5DRD3HSD17B1 | |
| SCHEMBL29439100 | 0.69 | HSD17B1 (0.64) | DRD1DRD2DRD5DRD3HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9429568-B2 | Silaanthracene as a red and near infrared sensor and a method to manufacture such a sensor | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY ON BEHALF OF SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) | 2016-08-30 | — | — | US | disclosed |
| US-9429568-B2 | Silaanthracene as a red and near infrared sensor and a method to manufacture such a sensor | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY ON BEHALF OF SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) | 2016-08-30 | — | — | US | disclosed |
| US-20150185209-A1 | BIOLOGICALLY ACTIVE COMPLEX AND ITS PREPARATION | SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150185209-A1 | BIOLOGICALLY ACTIVE COMPLEX AND ITS PREPARATION | SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150185209-A1 | BIOLOGICALLY ACTIVE COMPLEX AND ITS PREPARATION | PGLS, FOS, SPR | DRD1 4792/4885DRD2 4803/4885DRD5 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.