Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.59 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119554 | 0.98 | IP6K1 (0.61) | IP6K1AVPR2MYCNR4A1MEN1 | |
| SCHEMBL15923351 | 0.95 | MYC (0.57) | IP6K1AVPR2MYCNR4A1MEN1 | |
| SCHEMBL5063205 | 0.85 | AVPR2 (0.54) | IP6K1AVPR2MEN1KMT2AATM | |
| SCHEMBL15123245 | 0.85 | IP6K1 (0.66) | IP6K1MEN1KMT2AMRGPRX4ALDH1A1 | |
| SCHEMBL2088694 | 0.84 | ACLY (0.57) | MYCNR4A1MEN1KMT2AMAPT | |
| SCHEMBL14080465 | 0.84 | ADRB1 (0.63) | IP6K1MYCNR4A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15923279 | 0.84 | RAB9A (0.56) | IP6K1AVPR2MYCNR4A1ALDH1A1 | |
| SCHEMBL3823637 | 0.83 | KDM4E (0.58) | IP6K1AVPR2MYCNR4A1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL4890076 | 0.83 | ACLY (0.56) | MYCNR4A1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL15929282 | 0.83 | ADRB1 (0.61) | IP6K1MYCNR4A1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350311-B1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | MADRIGAL PHARMACEUTICALS INC (US) | 2013-12-25 | — | — | EP | claimed |
| EP-2350311-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | claimed |
| WO-2010056506-A1 | DIACYLGLYCEROL ACLYTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | claimed |
| US-20100113782-A1 | Diacylglycerol Acyltransferase Inhibitors | MADRIGAL PHARMACEUTICALS, INC. | 2010-05-06 | — | — | US | claimed |
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2020-08-06 | — | — | US | disclosed |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2019-05-09 | — | — | US | disclosed |
| US-9946847-B2 | Libraries of compounds having desired properties and methods for making and using them | BIOBLOCKS INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9946847-B2 | Libraries of compounds having desired properties and methods for making and using them | BIOBLOCKS INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2018-03-08 | — | — | US | disclosed |
| US-9815857-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9598443-B2 | Boron containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150361104-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2015-12-17 | — | — | US | disclosed |
| US-20150269356-A1 | LIBRARIES OF COMPOUNDS HAVING DESIRED PROPERTIES AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS INC (US) | 2015-09-24 | — | — | US | disclosed |
| US-20150269356-A1 | LIBRARIES OF COMPOUNDS HAVING DESIRED PROPERTIES AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS INC (US) | 2015-09-24 | — | — | US | disclosed |
| WO-2014121124-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014047463-A2 | LIBRARIES OF COMPOUNDS HAVING DESIRED PROPERTIES AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS, INC. (US) | 2014-03-27 | — | — | WO | disclosed |
| US-20100004221-A1 | THIAZEPINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2119719-A1 | THIAZEPINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004221-A1 | THIAZEPINE DERIVATIVE | HSD11B1, HSD17B1, HSD3B1 | IP6K1 2871/4885AVPR2 431/4885MYC 4154/4885 |
| US-20100113782-A1 | Diacylglycerol Acyltransferase Inhibitors | DGAT2, DGAT1, MOGAT2 | IP6K1 416/4885AVPR2 2841/4885MYC 2629/4885 |
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | IP6K1 1907/4885AVPR2 4212/4885MYC 2241/4885 |
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | IP6K1 1907/4885AVPR2 4212/4885MYC 2241/4885 |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | IP6K1 1907/4885AVPR2 4212/4885MYC 2241/4885 |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | IP6K1 1907/4885AVPR2 4212/4885MYC 2241/4885 |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | IP6K1 1907/4885AVPR2 4212/4885MYC 2241/4885 |
| US-20150361104-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | IP6K1 1907/4885AVPR2 4212/4885MYC 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.