Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562245 | 0.80 | PTGS2 (0.47) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3751941 | 0.79 | RAB9A (0.61) | RAB9ANPC1NOTUMMEN1KMT2A | |
| SCHEMBL9213944 | 0.79 | RAB9A (0.59) | RAB9ANPC1NOTUMMEN1KMT2A | |
| SCHEMBL18489825 | 0.78 | NPC1 (0.86) | RAB9ANPC1NOTUML3MBTL1MAPT | |
| SCHEMBL474171 | 0.76 | NOTUM (0.61) | RAB9ANPC1NOTUMMEN1KMT2A | |
| SCHEMBL2301990 | 0.76 | RAB9A (0.57) | RAB9ANPC1NOTUMMEN1KMT2A | |
| SCHEMBL6352556 | 0.76 | NPC1 (0.59) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20031207 | 0.73 | RAB9A (0.53) | RAB9ANPC1NOTUMMEN1KMT2A | |
| SCHEMBL541967 | 0.73 | NOTUM (0.72) | RAB9ANPC1NOTUMMEN1KMT2A | |
| SCHEMBL2609422 | 0.73 | RAB9A (0.53) | RAB9ANPC1NOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190071407-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2019-03-07 | — | — | US | disclosed |
| US-10155730-B2 | Isoxazoline derivatives as insecticides | SYNGENTA CROP PROTECTION, LLC (US) | 2018-12-18 | — | — | US | disclosed |
| US-20180244699-A1 | 1-HYDROXY-3H-2,1-BENZOXABOROLE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-30 | — | — | US | disclosed |
| EP-3337809-A1 | 1-HYDROXY-3H-2,1-BENZOXABOROLE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-2917201-B1 | DIHYDROTHIOPHENE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| US-9714228-B2 | Dihydrofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-25 | — | — | US | disclosed |
| WO-2017029289-A1 | 1-HYDROXY-3H-2,1-BENZOXABOROLE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-02-23 | — | — | WO | disclosed |
| EP-2755969-B1 | ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-18 | — | — | EP | disclosed |
| US-20170000133-A1 | BENZOXABOROLE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (SE) | 2017-01-05 | — | — | US | disclosed |
| US-20160368883-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2016-12-22 | — | — | US | disclosed |
| WO-2013026724-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| EP-2539330-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| US-20120329769-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2536698-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | Syngenta Participations AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| US-20120316124-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | disclosed |
| WO-2011101229-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011101402-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |
| EP-2356108-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055267-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-05-20 | — | — | WO | disclosed |
| CN-1098713-A | The ortho-ethenylphenylacetic acid derivatives that replaces | BASF AG (DE) | 1995-02-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329769-A1 | DIHYDROFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | FOXM1, NDUFC1, H1-0 | RAB9A 278/4885NPC1 725/4885NOTUM 1747/4885 |
| US-20180244699-A1 | 1-HYDROXY-3H-2,1-BENZOXABOROLE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | CBR3, HCRTR2, HCAR3 | RAB9A 2525/4885NPC1 1840/4885NOTUM 2367/4885 |
| US-20190071407-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | ACHE, CHRM1, ITPR3 | RAB9A 193/4885NPC1 1693/4885NOTUM 1682/4885 |
| US-20170000133-A1 | BENZOXABOROLE FUNGICIDES | CYP4X1, BROX, CYP1B1 | RAB9A 1828/4885NPC1 1614/4885NOTUM 877/4885 |
| US-10155730-B2 | Isoxazoline derivatives as insecticides | ACHE, CHRM1, ITPR3 | RAB9A 193/4885NPC1 1693/4885NOTUM 1682/4885 |
| US-20120316124-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | CHRM1, ACHE, P2RX7 | RAB9A 246/4885NPC1 1505/4885NOTUM 1853/4885 |
| US-20160368883-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | ACHE, CHRM1, ITPR3 | RAB9A 193/4885NPC1 1693/4885NOTUM 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.