Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | APEX1 | P27695 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596473 | 0.86 | ALOX15 (0.49) | TDP1MAPTKMT2AMEN1PTGS2 | |
| SCHEMBL2305253 | 0.84 | TDP1 (0.49) | TDP1KDM4EMAPK1SHBGMAPT | |
| SCHEMBL2306283 | 0.78 | HKDC1 (0.46) | TDP1KDM4EMAPK1SHBGMAPT | |
| SCHEMBL2311556 | 0.78 | SHBG (0.47) | TDP1KDM4EMAPK1SHBGMAPT | |
| SCHEMBL9192736 | 0.76 | LMNA (0.48) | TDP1KDM4EMAPK1MAPTKMT2A | |
| SCHEMBL10335356 | 0.76 | TYR (0.48) | TDP1MAPTRECQLKMT2ACYP2D6 | |
| SCHEMBL4596232 | 0.75 | ALDH1A1 (0.47) | TDP1KDM4EMAPK1MAPTRECQL | |
| SCHEMBL7201794 | 0.75 | THRA (0.44) | TDP1KDM4EMAPTRECQLKMT2A | |
| SCHEMBL4659818 | 0.74 | TYR (0.42) | TDP1KDM4EMAPK1MAPTRECQL | |
| SCHEMBL7950538 | 0.74 | RORC (0.47) | TDP1KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044593-A1 | CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | claimed |
| WO-2015035410-A1 | CANCER THERAPY | TRIACT THERAPEUTIC, INC. (US) | 2015-03-12 | — | — | WO | claimed |
| EP-2349235-A1 | USE OF CATECHOLIC BUTANE DERIVATIVES IN CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2011-08-03 | — | — | EP | claimed |
| WO-2010054264-A1 | USE OF CATECHOLIC BUTANE DERIVATIVES IN CANCER THERAPY | TRIACT THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | claimed |
| WO-1995000129-A1 | TREATMENT OF MULTIDRUG RESISTANT DISEASES | CHEMEX PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | claimed |
| EP-3044593-A1 | CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2961412-A1 | CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2015035410-A1 | CANCER THERAPY | TRIACT THERAPEUTIC, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2014134202-A1 | CANCER THERAPY | TRIACT THERAPEUTICS, INC. (US) | 2014-09-04 | — | — | WO | disclosed |
| EP-2349235-A1 | USE OF CATECHOLIC BUTANE DERIVATIVES IN CANCER THERAPY | Triact Therapeutics, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010054264-A1 | USE OF CATECHOLIC BUTANE DERIVATIVES IN CANCER THERAPY | TRIACT THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-1995000129-A1 | TREATMENT OF MULTIDRUG RESISTANT DISEASES | CHEMEX PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| EP-0288534-A4 | COMPOSITIONS OF CATECHOLIC BUTANES WITH ZINC. | CHEMEX PHARMACEUTICALS INC (US) | 1989-02-23 | — | — | EP | disclosed |
| EP-0288534-A1 | COMPOSITIONS OF CATECHOLIC BUTANES WITH ZINC. | CHEMEX PHARMACEUTICALS INC (US) | 1988-11-02 | — | — | EP | disclosed |
| WO-1988003026-A1 | COMPOSITIONS OF CATECHOLIC BUTANES WITH ZINC | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-05-05 | — | — | WO | disclosed |