SCHEMBL23069299

SCHEMBL23069299

O=C(OC[C@@]1(CO)COC[C@H](n2ccc(=O)[nH]c2=O)O1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ PRKCA P17252 9/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23244030 0.87 POLB (0.37) POLBHSD17B10PRKCA
SCHEMBL23243906 0.87 POLB (0.37) POLBHSD17B10PRKCA
SCHEMBL23243940 0.85 RNASE1 (0.53) PRKCA
SCHEMBL22110702 0.83 POLB (0.41) POLBHSD17B10PRKCA
SCHEMBL22009135 0.83 POLB (0.41) POLBHSD17B10PRKCA
SCHEMBL23069302 0.82 DUT (0.36) PRKCA
SCHEMBL22475062 0.82 PRKCA (0.41) POLBHSD17B10PRKCA
SCHEMBL23069416 0.81 SLC28A1 (0.36) —
SCHEMBL23244019 0.81 SLC28A1 (0.36) —
SCHEMBL29770533 0.80 POLB (0.37) POLBHSD17B10PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2026-04-16 — — US disclosed
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2024-11-14 — — US disclosed
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same SANOFI (FR) 2024-02-13 — — US disclosed
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-11-24 — — US disclosed
EP-4025582-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-07-13 — — EP disclosed
US-20210115075-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI (FR) 2021-04-22 — — US disclosed
WO-2021044004-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2021-03-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same RNMT, RRM2B, RRM2 POLB 124/4885HSD17B10 4591/4885PRKCA 3313/4885
US-20210115075-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, RRM2B, RRM2 POLB 124/4885HSD17B10 4591/4885PRKCA 3313/4885
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME NSUN2, NSUN3, SNRPA POLB 141/4885HSD17B10 4051/4885PRKCA 2266/4885
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, NSUN2, ADAR POLB 147/4885HSD17B10 4693/4885PRKCA 3297/4885
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS DCLRE1B, UPF1, IGF2BP1 POLB 58/4885HSD17B10 4320/4885PRKCA 3079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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