Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 7/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923371 | 0.79 | CALM1 (0.48) | ALDH1A1MAPTHPGDNPSR1IDH1 | |
| SCHEMBL5550889 | 0.78 | PLA2G2A (0.47) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL4937851 | 0.77 | PLA2G2A (0.44) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL28681774 | 0.76 | PLA2G2A (0.57) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL4937860 | 0.74 | PLA2G2A (0.44) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL5482150 | 0.74 | PLA2G2A (0.45) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL28180889 | 0.74 | ALDH1A1 (0.41) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL28180079 | 0.74 | USP2 (0.41) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL15621741 | 0.73 | PLA2G2A (0.50) | PLA2G2APLA2G10ALDH1A1USP2MAPT | |
| SCHEMBL5482149 | 0.73 | MYC (0.47) | PLA2G2APLA2G10ALDH1A1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200037-B2 | Compounds for control of appetite | UNIVERSITY OF CINCINNATI (US) | 2015-12-01 | — | — | US | disclosed |
| US-20140274887-A1 | Compounds for Control of Appetite | UNIVERSITY OF CINCINNATI | 2014-09-18 | — | — | US | disclosed |
| US-8729227-B2 | Compounds for control of appetite | UNIVERSITY OF CINCINNATI (US) | 2014-05-20 | — | — | US | disclosed |
| US-7994119-B2 | Neuropeptide Y receptor antagonists and agonists including O-glycosylated tripeptides, O-glycopeptides, and extended tripeptides; cardiovascular disorders | UNIVERSITY OF CINCINNATI (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090227519-A1 | COMPOUNDS FOR CONTROL OF APPETITE | UNIVERSITY OF CINCINNATI (US) | 2009-09-10 | — | — | US | disclosed |
| US-7465710-B2 | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm | UNIVERSITY OF CINCINNATI (US) | 2008-12-16 | — | — | US | disclosed |
| US-20080221038-A1 | Compounds for Control of Appetite | THE UNIVERSITY OIF CINCINNATI (US) | 2008-09-11 | — | — | US | disclosed |
| US-20070197445-A1 | Neuropeptide Y receptor antagonists and agonists including O-glycosylated tripeptides, O-glycopeptides, and extended tripeptides; cardiovascular disorders; pancreatic polypeptide; peptide yy; pancreatitis; liver disorders | UNIVERSITY OF CINCINNATI (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2006020207-A2 | COMPOUNDS FOR CONTROL OF APPETITE | UNIVERSITY OF CINCINNATI (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060009395-A1 | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm | UNIVERSITY OF CINCINNATI (US) | 2006-01-12 | — | — | US | disclosed |
| US-6962902-B2 | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm | UNIVERSITY OF CINCINNATI (US) | 2005-11-08 | — | — | US | disclosed |
| US-20040209820-A1 | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm | UNIVERSITY OF CINCINNATI | 2004-10-21 | — | — | US | disclosed |
| US-6737408-B1 | DIPEPTIDE AND TRIPEPTIDE DERIVATIVES | UNIVERSITY OF CINCINNATI | 2004-05-18 | — | — | US | disclosed |
| US-6235718-B1 | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm | THE UNIVERSITY OF CINCINNATI | 2001-05-22 | — | — | US | disclosed |
| US-6013633-A | ADMINISTERING DIPEPTIDES AND TRIPEPTIDES | UNIVERSITY OF CINCINNATI (US) | 2000-01-11 | — | — | US | disclosed |
| US-4686283-A | POLYPEPTIDES | SYNTEX (U.S.A.) INC. (US) | 1987-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197445-A1 | Neuropeptide Y receptor antagonists and agonists including O-glycosylated tripeptides, O-glycopeptides, and extended tripeptides; cardiovascular disorders; pancreatic polypeptide; peptide yy; pancreatitis; liver disorders | NPY4R, NPY2R, NPY1R | PLA2G2A 2516/4885PLA2G10 1916/4885ALDH1A1 4490/4885 |
| US-20090227519-A1 | COMPOUNDS FOR CONTROL OF APPETITE | NPY4R, NPY2R, NPY1R | PLA2G2A 1581/4885PLA2G10 1115/4885ALDH1A1 4777/4885 |
| US-20080221038-A1 | Compounds for Control of Appetite | NPY4R, NPY1R, NPY2R | PLA2G2A 3977/4885PLA2G10 3265/4885ALDH1A1 4771/4885 |
| US-20140274887-A1 | Compounds for Control of Appetite | NPY4R, NPY2R, NPY1R | PLA2G2A 1663/4885PLA2G10 1065/4885ALDH1A1 4786/4885 |
| US-20060009395-A1 | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm | NPPA, NPR3, NPR1 | PLA2G2A 4081/4885PLA2G10 2109/4885ALDH1A1 4003/4885 |
| US-20040209820-A1 | Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm | NPPA, NPR3, NPR1 | PLA2G2A 4081/4885PLA2G10 2109/4885ALDH1A1 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.