SCHEMBL23360809

SCHEMBL23360809

CCCCCC(Cl)S(=O)(=O)[O-].[Na+]

nearest known ligand 0.41

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.41
CA2 known ✓ P00918 2/20 0.39
FDPS known ✓ P14324 4/20 0.34
NR1I2 O75469 1/20 0.41
RECQL P46063 2/20 0.41
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
EPHX2 P34913 1/20 0.41
TP53 P04637 1/20 0.41
BLM P54132 1/20 0.41
NFKB1 P19838 1/20 0.37
GPR84 Q9NQS5 4/20 0.36
OPRM1 P35372 1/20 0.34
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11223474 0.98 RECQL (0.44) NR1I2RECQLCA1GLAHPGD
SCHEMBL17710323 0.93 CA2 (0.38) NR1I2RECQLCA1GLAHPGD
SCHEMBL3381883 0.77 CA2 (0.47) NR1I2RECQLCA1GLAHPGD
SCHEMBL9660940 0.76 RECQL (0.47) NR1I2RECQLCA1GLAHPGD
SCHEMBL9756753 0.76 RECQL (0.47) NR1I2RECQLCA1GLAHPGD
SCHEMBL28620924 0.76 RECQL (0.47) NR1I2RECQLCA1GLAHPGD
SCHEMBL3386052 0.76 CA2 (0.50) NR1I2RECQLCA1GLAHPGD
SCHEMBL17219439 0.76 RECQL (0.47) NR1I2RECQLCA1GLAHPGD
SCHEMBL17336061 0.76 RECQL (0.47) NR1I2RECQLCA1GLAHPGD
SCHEMBL8688848 0.76 RECQL (0.47) NR1I2RECQLCA1GLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112795002-B Polyether anionic and nonionic surfactant containing heteroatom and preparation method thereof 中国石油化工股份有限公司 2022-04-01 CN disclosed
WO-2021093601-A1 SURFACTANT AND PREPARATION METHOD THEREFOR 中国石油化工股份有限公司 2021-05-20 WO disclosed
CN-112795002-A Alkoxy polyether anionic and nonionic surfactant containing heteroatom and preparation method thereof 中国石油化工股份有限公司 2021-05-14 CN disclosed