SCHEMBL2350583

SCHEMBL2350583

CC(C)NC(=O)NC(=N)Nc1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
CNR1 P21554 3/20 0.47
GAA P10253 1/20 0.47
PKM P14618 1/20 0.47
RAB9A P51151 4/20 0.45
NPC1 O15118 4/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
HTT P42858 2/20 0.45
MAPT P10636 2/20 0.45
NLRP1 Q9C000 1/20 0.45
LMNA P02545 3/20 0.45
FPR2 P25090 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
EPHX1 P07099 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Proguanil SCHEMBL45726 0.85 LMNA (0.41) ALDH1A1CNR1GAAPKMRAB9A
Proguanil SCHEMBL2539379 0.85 MEN1 (0.46) ALDH1A1CNR1GAARAB9ANPC1
Proguanil SCHEMBL2543837 0.84 LMNA (0.40) ALDH1A1CNR1GAAPKMRAB9A
Proguanil SCHEMBL218859 0.84 LMNA (0.40) ALDH1A1CNR1GAAPKMRAB9A
SCHEMBL13754433 0.83 CNR1 (0.66) ALDH1A1CNR1GAAPKMRAB9A
SCHEMBL1989233 0.83 ALDH1A1 (0.44) ALDH1A1CNR1GAARAB9ANPC1
SCHEMBL10753026 0.81 MDM2 (0.50) RAB9AMEN1KMT2ALMNAEPHX1
Benzene SCHEMBL11581005 0.80 CNR1 (0.62) ALDH1A1CNR1GAAPKMRAB9A
Proguanil SCHEMBL9247094 0.80 MEN1 (0.40) ALDH1A1CNR1RAB9ANPC1MEN1
Proguanil SCHEMBL2545386 0.80 ALDH1A1 (0.43) ALDH1A1CNR1GAARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3457850-B1 SYNERGISTIC COMBINATION OF BIOCIDES ARXADA LLC (US) 2025-12-17 EP disclosed
US-20230247989-A1 Synergistic Biocide Composition With a Polyglycerol Ester ARCH UK BIOCIDES LTD (GB) 2023-08-10 US disclosed
US-20200305435-A1 SYNERGISTIC COMBINATION OF BIOCIDES Arxada, LLC 2020-10-01 US disclosed
EP-3457850-A1 SYNERGISTIC COMBINATION OF BIOCIDES Lonza Inc. (US) 2019-03-27 EP disclosed
WO-2017222965-A1 SYNERGISTIC COMBINATION OF BIOCIDES LONZA INC. (US) 2017-12-28 WO disclosed
US-20110206770-A1 ATOVAQUONE WITH A PARTICLE SIZE DIAMETER RANGE (D90) OF GREATER THAN 3 MICRONS TO ABOUT 10 MICRONS Alphapharm Pty. Ltd. (AU) 2011-08-25 US disclosed
US-20090280069-A1 PROGUANIL TO TREAT SKIN/MUCOSAL DISEASES TOLMAR, INC. (US) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200305435-A1 SYNERGISTIC COMBINATION OF BIOCIDES POLR1C, BTD, UNG ALDH1A1 1099/4885CNR1 4771/4885GAA 277/4885
US-20090280069-A1 PROGUANIL TO TREAT SKIN/MUCOSAL DISEASES PROKR1, PROKR2, MC1R ALDH1A1 4208/4885CNR1 1105/4885GAA 1231/4885
US-20110206770-A1 ATOVAQUONE WITH A PARTICLE SIZE DIAMETER RANGE (D90) OF GREATER THAN 3 MICRONS TO ABOUT 10 MICRONS NDUFA10, NDUFB10, DHODH ALDH1A1 791/4885CNR1 4721/4885GAA 1487/4885
US-20230247989-A1 Synergistic Biocide Composition With a Polyglycerol Ester MGLL, PLD3, PHOSPHO1 ALDH1A1 2216/4885CNR1 4759/4885GAA 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.