Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nitrophenolate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrophenolate SCHEMBL27998915 | 1.00 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL29757972 | 1.00 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL28179749 | 0.98 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL28930677 | 0.95 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL3892329 | 0.95 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL10496079 | 0.95 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL3898213 | 0.95 | HSD17B10 (0.54) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL28214763 | 0.89 | ALDH1A1 (0.47) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL17275508 | 0.88 | GPR35 (0.50) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Nitrophenolate SCHEMBL30910022 | 0.88 | GPR35 (0.53) | HSD17B10TDP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2001 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120982357-B | Breeding method of plug rock wool cutting hops | Jiangsu Yuntai Farm Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122030202-A | High-yield disease-reducing efficient planting method for large tomato seedling transplanting in North China | 河北省农林科学院农业信息与经济研究所 | 2026-05-15 | — | — | CN | claimed |
| CN-122004086-A | Flower promoting method of golden camellia | 广西壮族自治区南宁良凤江国家森林公园 | 2026-05-12 | — | — | CN | claimed |
| CN-120188792-A | Rice bakanae disease prevention and treatment medicine and preparation method thereof | 江西省农业科学院植物保护研究所 | 2025-06-24 | — | — | CN | claimed |
| CN-117730725-B | Breeding method for citrus unshiu seedlings | 南宁市农业科学研究所(南宁市蔬菜研究所、南宁市农产品质量安全检测中心) | 2025-06-17 | — | — | CN | claimed |
| CN-120130308-A | Soilless breeding method of drynaria rhizome | 吉安市林业科学研究所(吉安市青原山试验林场) | 2025-06-13 | — | — | CN | claimed |
| CN-117084114-B | Indocalamus penis section seedling raising method | 湖南省林业科学院 | 2025-06-10 | — | — | CN | claimed |
| CN-120052217-A | Cultivation and planting method of konjak | 陕西安康鲤鱼山生态农业科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120036340-A | Composition for preventing root rot of lysimachia christinae hance and application method thereof | 海南茗卉农林科技发展有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-116250446-B | Method for improving seedling grafting survival rate and promoting root system development | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | 2025-05-27 | — | — | CN | claimed |
| US-20120128648-A1 | Novel Biopesticide Compositions And Method For Isolation And Characterization Of Same | THE ENERGY AND RESOURCES INSTITUTE (TERI) (IN) | 2012-05-24 | — | — | US | claimed |
| US-20120004104-A1 | OIL DISPERSIONS OF nAChR BINDING NEONICOTINOIDS | GAT MICROENCAPSULATION AG (AT) | 2012-01-05 | — | — | US | claimed |
| WO-2010099965-A2 | OIL DISPERSIONS OF NACHR BINDING NEONICOTINOIDS | GAT MICROENCAPSULATION AG (AT) | 2010-09-10 | — | — | WO | claimed |
| EP-2225940-A1 | Oil dispersions of nAChR binding neonicotinoids | GAT Microencapsulation AG (AT) | 2010-09-08 | — | — | EP | claimed |
| US-20090053271-A1 | Reverse-Phase Microcapsules for Actice Ingredients, Simplified Process of Manufacture Thereof and Combined Formulation Wdg- Cs,Zc, Ec-Sc, and Cx | FMC CORPORATION | 2009-02-26 | — | — | US | claimed |
| EP-2004718-A1 | REVERSE-PHASE MICROCAPSULES FOR ACTIVE INGREDIENTS, SIMPLIFIED PROCESS OF MANUFACTURE THEREOF AND COMBINED FORMULATIONS WDG-CS, ZC, EC-SC AND CX | GAT Microencapsulation AG (AT) | 2008-12-24 | — | — | EP | claimed |
| WO-2007112933-A1 | REVERSE-PHASE MICROCAPSULES FOR ACTIVE INGREDIENTS, SIMPLIFIED PROCESS OF MANUFACTURE THEREOF AND COMBINED FORMULATIONS WDG-CS, ZC, EC-SC AND CX | GAT MICROENCAPSULATION AG (AT) | 2007-10-11 | — | — | WO | claimed |
| US-6232270-B1 | ENHANCER COMPONENT CONTAINING A SUBSTANTIALLY PURE BACTERIAL CULTURE, SUSPENSION, SPORES, OR CELLS OF A BACTERIA SELECTED FROM THE GENUS BACILLUS OR A SOIL BACTERIA. | MICRO FLO COMPANY | 2001-05-15 | — | — | US | claimed |
| US-5525576-A | CARBOHYDRATES AND POLYHYDROXYCARBOXYLIC ACIDS OBTAINED BY THE OXIDATION OF A HULL-FREE PENTOSE-CONTAINING EXTRACT; ENHANCED ABSORPTION OF PLANT GROWTH REGULATORS, INSECTICIDES, FUNGICIDES AND PESTICIDES | MEDINA-VEGA LUIS R (US) | 1996-06-11 | — | — | US | claimed |
| US-4151165-A | USING AN AROMATIC NITRO COMPOUND IN OXYGEN-FREE, AQUEOUS ENVIRONMENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-04-24 | — | — | US | claimed |