SCHEMBL2352487

SCHEMBL2352487

CCCCC(C)c1ccccc1OO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
PPARG P37231 3/20 0.38
PTGES O14684 1/20 0.38
ALOX5 P09917 1/20 0.38
PPARA Q07869 1/20 0.38
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ATM Q13315 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 2/20 0.36
RECQL P46063 1/20 0.36
NR1I2 O75469 1/20 0.36
LMNA P02545 1/20 0.36
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36
MAPT P10636 1/20 0.36
OPRK1 P41145 1/20 0.36
HTR2B P41595 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2352057 0.89 TSHR (0.41) TSHRPPARGKDM4EL3MBTL1ATM
SCHEMBL6683928 0.86 TSHR (0.43) TSHRPPARGALOX5PPARAKDM4E
SCHEMBL5853299 0.83 LTA4H (0.46) PPARGPTGESALOX5PPARAKDM4E
SCHEMBL29245173 0.82 PPARG (0.36) TSHRPPARGPTGESALOX5PPARA
SCHEMBL190108 0.82 TSHR (0.59) TSHRPPARAKDM4EL3MBTL1ATM
SCHEMBL6685019 0.81 TSHR (0.45) TSHRKDM4EMEN1KMT2ACYP3A4
SCHEMBL25277363 0.81 KDM4E (0.46) TSHRPPARGPTGESALOX5PPARA
SCHEMBL980542 0.81 TSHR (0.46) TSHRPPARGPTGESALOX5PPARA
SCHEMBL6686117 0.81 PPARG (0.44) TSHRPPARGALOX5KDM4EL3MBTL1
SCHEMBL2697201 0.80 KDM4E (0.36) TSHRPPARGPTGESALOX5PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352715-A1 PROCESS FOR PRODUCING PHENOL Exxonmobil Chemical Company (US) 2011-08-10 EP claimed
US-20110190546-A1 Process For Producing Phenol EXXONMOBIL CHEMICAL PATENTS INC. 2011-08-04 US claimed
WO-2010042261-A1 PROCESS FOR PRODUCING PHENOL EXXONMOBIL CHEMICAL COMPANY (US) 2010-04-15 WO claimed
US-9249078-B2 Mixed metal oxide catalysts and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-02-02 US disclosed
US-9238605-B2 Oxidation of hydrocarbons EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-01-19 US disclosed
US-20150225326-A1 Oxidation of Hydrocarbons EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-08-13 US disclosed
US-20150148567-A1 MIXED METAL OXIDE CATALYSTS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-28 US disclosed
WO-2014039653-A2 OXIDATION OF HYDROCARBONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-03-13 WO disclosed
US-8445730-B2 Process for producing phenol EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-05-21 US disclosed
WO-2013052217-A2 MIXED METAL OXIDE CATALYSTS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-11 WO disclosed
EP-2352715-A1 PROCESS FOR PRODUCING PHENOL Exxonmobil Chemical Company (US) 2011-08-10 EP disclosed
US-20110190546-A1 Process For Producing Phenol EXXONMOBIL CHEMICAL PATENTS INC. 2011-08-04 US disclosed
WO-2010042261-A1 PROCESS FOR PRODUCING PHENOL EXXONMOBIL CHEMICAL COMPANY (US) 2010-04-15 WO disclosed
US-4487970-A ANTIMONY PENTAFLUORIDE AND GRAPHITE CATALYST PHILLIPS PETROLEUM COMPANY (US) 1984-12-11 US disclosed
US-4482757-A Cleavage of hydroperoxides PHILLIPS PETROLEUM COMPANY (US) 1984-11-13 US disclosed
US-4480141-A SENCONDARY ALKYL-SUBSTITUTED HYDROPEROXIDES ARE CLEAVED TO PHENOLS AND KETONES WITH BORON PHOSPHATE CATALYST PHILLIPS PETROLEUM COMPANY (US) 1984-10-30 US disclosed
US-4450303-A IN PRESENCE OF OXYGEN AND SAMARIN SALT PHILLIPS PETROLEUM COMPANY (US) 1984-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148567-A1 MIXED METAL OXIDE CATALYSTS AND USE THEREOF SOD1, SOD3, LPO TSHR 2481/4885PPARG 2731/4885PTGES 1724/4885
US-20150225326-A1 Oxidation of Hydrocarbons HAO2, HMOX2, HMOX1 TSHR 2794/4885PPARG 585/4885PTGES 188/4885
US-20110190546-A1 Process For Producing Phenol CYP1A1, PAH, MYB TSHR 1222/4885PPARG 423/4885PTGES 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.