Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536283 | 0.81 | MCOLN2 (0.44) | ALDH1A1TP53SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL23536308 | 0.78 | TP53 (0.42) | ALDH1A1TP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL23536339 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL23536015 | 0.72 | PAX8 (0.37) | HTR2AHTR2CKDM4ELMNAL3MBTL1 | |
| SCHEMBL23536173 | 0.71 | TP53 (0.44) | ALDH1A1TP53SMN1; SMN2KMT2APOLB | |
| SCHEMBL23536098 | 0.71 | TP53 (0.44) | ALDH1A1TP53SMN1; SMN2POLBKDM4E | |
| SCHEMBL23043638 | 0.70 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2APOLBKDM4E | |
| SCHEMBL23536231 | 0.69 | POLB (0.59) | ALDH1A1TP53SMN1; SMN2KMT2APOLB | |
| SCHEMBL23536515 | 0.67 | MEN1 (0.34) | KDM4ELMNAL3MBTL1PAX8RORC | |
| SCHEMBL23536202 | 0.66 | MAPT (0.40) | ALDH1A1TP53SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |