Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13365039 | 0.89 | PKM (0.38) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL11899399 | 0.89 | PKM (0.43) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL2362708 | 0.87 | L3MBTL1 (0.37) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL2362702 | 0.85 | MEN1 (0.38) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL28015263 | 0.83 | POLB (0.39) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL4218277 | 0.83 | MAPT (0.39) | PKMMAPTL3MBTL1POLBTDP1 | |
| SCHEMBL19615372 | 0.81 | MAPT (0.39) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL8304642 | 0.81 | KDM4E (0.43) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL32691277 | 0.81 | POLB (0.38) | PKMNPC1MAPTL3MBTL1POLB | |
| SCHEMBL16626084 | 0.80 | PKM (0.50) | PKMNPC1MAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2686303-B1 | N-(3-CARBAMOYLPHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THEIR USE FOR COMBATING ANIMAL PESTS | BAYER IP GMBH (DE) | 2016-01-20 | — | — | EP | disclosed |
| EP-2686303-B1 | N-(3-CARBAMOYLPHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THEIR USE FOR COMBATING ANIMAL PESTS | BAYER IP GMBH (DE) | 2016-01-20 | — | — | EP | disclosed |
| US-9126945-B2 | N-(3-carbamoylphenly)-1H-pyrazole-5-carboxamide derivatives and the use thereof for controlling animal pests | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-9126945-B2 | N-(3-carbamoylphenly)-1H-pyrazole-5-carboxamide derivatives and the use thereof for controlling animal pests | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| CN-102317263-B | Halogen substituted compounds as pesticides | BAYER IP GMBH | 2015-04-22 | — | — | CN | disclosed |
| US-20150099766-A1 | Novel halogen-substituted compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-09 | — | — | US | disclosed |
| US-8946234-B2 | Halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-20140088153-A1 | N-(3-CARBAMOYLPHENLY)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| US-20140088153-A1 | N-(3-CARBAMOYLPHENLY)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
| WO-2012126766-A1 | N-(3-CARBAMOYLPHENYL)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2012-09-27 | — | — | WO | disclosed |
| US-20110301181-A1 | halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | US | disclosed |
| EP-2352723-A2 | HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010133312-A1 | HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133312-A1 | HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301181-A1 | halogen-substituted compounds | L3MBTL4, QSOX1, L3MBTL3 | PKM 2622/4885NPC1 2312/4885MAPT 4184/4885 |
| US-20150099766-A1 | Novel halogen-substituted compounds | L3MBTL4, PRDX4, PRDX1 | PKM 3155/4885NPC1 2168/4885MAPT 4164/4885 |
| US-20140088153-A1 | N-(3-CARBAMOYLPHENLY)-1H-PYRAZOLE-5-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF FOR CONTROLLING ANIMAL PESTS | CBR3, CYCS, CAT | PKM 1286/4885NPC1 4048/4885MAPT 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.