SCHEMBL2363740

SCHEMBL2363740

C=CCN(CC=C)CCCCCCO

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 2/20 0.31
TSHR P16473 2/20 0.31
OPRM1 P35372 2/20 0.31
OPRD1 P41143 2/20 0.31
OPRK1 P41145 2/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5399561 1.00 KDM4E (0.33) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3806768 1.00 KDM4E (0.33) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL7057032 1.00 KDM4E (0.33) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL4411839 0.98 KDM4E (0.33) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL2363817 0.95 OPRM1 (0.34) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL2363335 0.95 OPRM1 (0.34) MEN1KMT2AALDH1A1LMNATSHR
SCHEMBL2363490 0.93 OPRM1 (0.35) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL2733647 0.90 ALDH1A1 (0.34) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3655351 0.87 KDM4E (0.33) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3060057 0.87 KDM4E (0.33) KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2183228-A1 CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1 Vitae Pharmaceuticals, Inc. (US) 2010-05-12 EP claimed
US-7605107-B2 Method of preparing a supported hydrotreating catalyst EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-10-20 US claimed
US-7538066-B2 Method of preparing a hydrotreating catalyst on a support containing a rare earth metal EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-05-26 US claimed
WO-2009017664-A1 CYCLIC INHIBITORS OF 11β-HYDROXYSTERIOD DEHYDROGENASE 1 VITAE PHARMACEUTICALS, INC. (US) 2009-02-05 WO claimed
US-20070082811-A1 Method of preparing a hydrotreating catalyst on a support containing a rare earth metal EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-04-12 US claimed
US-20070072765-A1 Method of preparing a supported hydrotreating catalyst EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-03-29 US claimed
EP-3053944-B1 METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR SHINETSU CHEMICAL CO (JP) 2021-10-06 EP disclosed
US-10472377-B2 Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-11-12 US disclosed
EP-2531480-B1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-01-16 EP disclosed
US-20170275305-A1 METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR SHINETSU CHEMICAL CO (JP) 2017-09-28 US disclosed
US-20170275305-A1 METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR SHINETSU CHEMICAL CO (JP) 2017-09-28 US disclosed
US-9708350-B2 Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-07-18 US disclosed
US-9708350-B2 Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-07-18 US disclosed
EP-2531480-A1 DEHYDROGENATION PROCESS ExxonMobil Chemical Patents Inc. (US) 2012-12-12 EP disclosed
US-20120302798-A1 Dehydrogenation Process EXXONMOBIL CHEMICAL PATENTS INC. 2012-11-29 US disclosed
US-20120271077-A1 Dehydrogenation Process EXXONMOBILE CHEMICAL PATENTS INC. (US) 2012-10-25 US disclosed
WO-2012050665-A1 PROCESS FOR PRODUCING PHENOL EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-19 WO disclosed
WO-2011096992-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed
WO-2011096997-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed
WO-2011096994-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170275305-A1 METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR ADH1A, ADH1C, AP3M1 KDM4E 2409/4885MEN1 3250/4885KMT2A 1405/4885
US-10472377-B2 Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator ADH1A, ADH1C, AP3M1 KDM4E 2409/4885MEN1 3250/4885KMT2A 1405/4885
US-20120271077-A1 Dehydrogenation Process ADH5, ADH1A, ADH1C KDM4E 2118/4885MEN1 3747/4885KMT2A 2800/4885
US-20120302798-A1 Dehydrogenation Process NDUFV1, NDUFV2, MAFG KDM4E 537/4885MEN1 1335/4885KMT2A 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.