SCHEMBL2363490

SCHEMBL2363490

C=CCN(CCCCO)CCCCO

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.35
OPRD1 P41143 4/20 0.35
OPRK1 P41145 4/20 0.35
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.32
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2363817 0.98 OPRM1 (0.34) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL2363335 0.98 OPRM1 (0.34) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL4411839 0.95 KDM4E (0.33) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL7057032 0.93 KDM4E (0.33) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL2363740 0.93 KDM4E (0.33) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL3806768 0.93 KDM4E (0.33) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL5399561 0.93 KDM4E (0.33) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL2363876 0.92 OPRM1 (0.36) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL3430771 0.88 OPRM1 (0.34) OPRM1OPRD1OPRK1ALDH1A1TSHR
SCHEMBL2733647 0.87 ALDH1A1 (0.34) OPRM1OPRD1OPRK1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718564-B2 Partially decomposed catalyst and hydrocarbon oxidation processes using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-05-18 US claimed
US-7605107-B2 Method of preparing a supported hydrotreating catalyst EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-10-20 US claimed
US-7538066-B2 Method of preparing a hydrotreating catalyst on a support containing a rare earth metal EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-05-26 US claimed
US-20070082811-A1 Method of preparing a hydrotreating catalyst on a support containing a rare earth metal EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-04-12 US claimed
US-20070072765-A1 Method of preparing a supported hydrotreating catalyst EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-03-29 US claimed
EP-2531480-B1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-01-16 EP disclosed
US-9035107-B2 Dehydrogenation process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-19 US disclosed
US-9024078-B2 Dehydrogenation process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-05 US disclosed
US-8969639-B2 Dehydrogenation process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US disclosed
US-8884075-B2 Process for producing phenol EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-11-11 US disclosed
US-20140148620-A1 Process for Producing Phenol EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-05-29 US disclosed
US-20120323046-A1 Dehydrogenation Process EXXONMOBIL CHEMICAL PATENTS INC. 2012-12-20 US disclosed
US-20120302798-A1 Dehydrogenation Process EXXONMOBIL CHEMICAL PATENTS INC. 2012-11-29 US disclosed
US-20120271077-A1 Dehydrogenation Process EXXONMOBILE CHEMICAL PATENTS INC. (US) 2012-10-25 US disclosed
WO-2012050665-A1 PROCESS FOR PRODUCING PHENOL EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-19 WO disclosed
WO-2011096992-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed
WO-2011096997-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed
WO-2011096994-A1 DEHYDROGENATION PROCESS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-11 WO disclosed
US-7718564-B2 Partially decomposed catalyst and hydrocarbon oxidation processes using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-05-18 US disclosed
US-20060293544-A1 Partially decomposed catalyst and hydrocarbon oxidation processes using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2006-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140148620-A1 Process for Producing Phenol HPD, CYP2J2, CYP2E1 OPRM1 2691/4885OPRD1 1395/4885OPRK1 1094/4885
US-20120271077-A1 Dehydrogenation Process ADH5, ADH1A, ADH1C OPRM1 1631/4885OPRD1 528/4885OPRK1 1174/4885
US-20120302798-A1 Dehydrogenation Process NDUFV1, NDUFV2, MAFG OPRM1 2532/4885OPRD1 1453/4885OPRK1 1981/4885
US-20120323046-A1 Dehydrogenation Process ADH1A, ADH5, ADH1C OPRM1 1061/4885OPRD1 373/4885OPRK1 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.