SCHEMBL23723317

SCHEMBL23723317

O=C(CN1CCC[C@@H]1C(=O)O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
HPGD P15428 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP1A2 P05177 1/20 0.51
CTSK P43235 6/20 0.51
CYP2C19 P33261 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
PREP P48147 1/20 0.44
FAP Q12884 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12634745 1.00 ALDH1A1 (0.52) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL12302263 1.00 ALDH1A1 (0.52) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL20248643 0.95 ALDH1A1 (0.57) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL8546917 0.91 RAB9A (0.50) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL12634763 0.88 CTSK (0.52) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL12634718 0.88 CTSK (0.52) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL16307617 0.88 POLB (0.53) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL16307618 0.85 CTSK (0.53) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL12137390 0.85 ALDH1A1 (0.48) ALDH1A1KDM4EMEN1HPGDKMT2A
SCHEMBL18352761 0.84 LTA4H (0.55) ALDH1A1KDM4EMEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606543-B2 Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto MINDSET PHARMA INC. (CA) 2026-04-21 US disclosed
US-20250250256-A1 INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO MINDSET PHARMA INC. (CA) 2025-08-07 US disclosed
WO-2023201423-A1 INDOLINE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO MINDSET PHARMA INC. (CA) 2023-10-26 WO disclosed
EP-4100403-A1 3-PYRROLIDINE-INDOLE DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS Mindset Pharma Inc. (CA) 2022-12-14 EP disclosed
WO-2021155467-A1 3-PYRROLIDINE-INDOLE DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS MINDSET PHARMA INC. (CA) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250250256-A1 INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO TPH1, TPH2, HTR5A ALDH1A1 1619/4885KDM4E 4240/4885MEN1 2490/4885
US-12606543-B2 Indole derivatives as serotonergic agents useful for the treatment of disorders related thereto HTR6, CNR1, HTR3C ALDH1A1 1626/4885KDM4E 4090/4885MEN1 3163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.