Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 4/20 | 0.31 |
| ▸ | BRAF | P15056 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770748 | 0.91 | RORC (0.33) | RORCTACR1 | |
| SCHEMBL23770643 | 0.85 | ADRB2 (0.37) | ABL1WDR5RAF1BRAF | |
| SCHEMBL23770705 | 0.85 | HRH3 (0.35) | WDR5 | |
| SCHEMBL23770589 | 0.84 | WDR5 (0.31) | WDR5 | |
| SCHEMBL23770744 | 0.84 | RAF1 (0.33) | ABL1WDR5RAF1BRAF | |
| SCHEMBL19925185 | 0.83 | RORC (0.35) | ABL1RORCWDR5RAF1BRAF | |
| SCHEMBL29464968 | 0.83 | RORC (0.35) | ABL1RORCWDR5RAF1BRAF | |
| SCHEMBL23770477 | 0.83 | MAPK10 (0.36) | RORCBRAF | |
| SCHEMBL23770780 | 0.82 | PRKCA (0.33) | RORC | |
| SCHEMBL23770679 | 0.81 | TTR (0.32) | ABL1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |