Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Nitrous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL11219505 | 1.00 | ALDH1A1 (1.00) | — | |
| Nitrous Acid SCHEMBL8933907 | 1.00 | — | — | |
| Nitrous Acid SCHEMBL9079679 | 1.00 | ALDH1A1 (1.00) | — | |
| Nitrous Acid SCHEMBL341 | 1.00 | — | — | |
| Nitrous Acid SCHEMBL4730863 | 0.94 | — | — | |
| Nitrous Acid SCHEMBL2377993 | 0.94 | ALDH1A1 (0.88) | — | |
| Nitrous Acid SCHEMBL10973177 | 0.94 | ALDH1A1 (0.88) | — | |
| Nitrous Acid SCHEMBL2716956 | 0.94 | ALDH1A1 (0.88) | — | |
| Nitrous Acid SCHEMBL8638727 | 0.94 | — | — | |
| Nitrous Acid SCHEMBL609796 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118993926-A | Preparation method of chiral amino acid | 香港大学 | 2024-11-22 | — | — | CN | disclosed |
| US-20240383842-A1 | METHODS OF PREPARING CHIRAL AMINO ACIDS | Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) | 2024-11-21 | — | — | US | disclosed |
| US-20230414791-A1 | NON-METALLIC MAGNETIC RESONANCE CONTRAST AGENT | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2023-12-28 | — | — | US | disclosed |
| US-11771779-B2 | Non-metallic magnetic resonance contrast agent | HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED (IL) | 2023-10-03 | — | — | US | disclosed |
| CN-114368762-B | Exogenous source 15 NO donor sodium nitroprusside [ ] 15 Synthesis method of NO) | 上海化工研究院有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-110763535-B | Sample preparation method for measuring nitrite nitrogen 15 isotopic abundance | 上海化工研究院有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-114368762-A | External source15NO donor sodium nitroprusside-, (ii)15NO) Synthesis method | 上海化工研究院有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-9673030-B2 | Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry | EMORY UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |