SCHEMBL239222

SCHEMBL239222

OCCCC(CCCO)CCCO

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
LMNA P02545 3/20 0.36
TSHR P16473 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
THRB P10828 1/20 0.32
CAMK2A Q9UQM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6577653 0.93 THRB (0.35) ALDH1A1LMNATSHRSMN1; SMN2THRB
SCHEMBL9702342 0.85 LMNA (0.46) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL4882493 0.85 LMNA (0.52) ALDH1A1LMNATSHRSMN1; SMN2THRB
SCHEMBL6925076 0.85 LMNA (0.46) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL15027 0.85
SCHEMBL236338 0.84 ALDH1A1 (0.47) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL7288108 0.84 ALDH1A1 (0.59) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL8996397 0.84 ALDH1A1 (0.47) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL6441220 0.84 ALDH1A1 (0.59) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL21067647 0.82 LMNA (0.38) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117844431-A Thermoplastic polyurethane adhesive, preparation method and application thereof 万华化学集团股份有限公司 2024-04-09 CN claimed
CN-114316197-B Thermoplastic polyurethane adhesive with low polarity and high heat resistance and application thereof 万华化学集团股份有限公司 2023-07-14 CN claimed
CN-114316197-A Low-polarity high-heat-resistance thermoplastic polyurethane adhesive and application thereof 万华化学集团股份有限公司 2022-04-12 CN claimed
US-8278451-B2 Pseudoazulenyl nitrones THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2012-10-02 US claimed
US-8173630-B2 Multipodal tethers for high-density attachment of redox-active moieties to substrates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-08 US claimed
US-20100016349-A1 PSEUDOAZULENYL NITRONES THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2010-01-21 US claimed
WO-2008002614-A2 PSEUDOAZULENYL NITRONES THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2008-01-03 WO claimed
EP-0779888-B1 PYRIMIDO [5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM BOEHRINGER INGELHEIM PHARMA (DE) 1999-04-28 EP claimed
US-5707989-A ANTITUMOR AGENTS, INHIBITING SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES DR. KARL THOMAE GMBH (DE) 1998-01-13 US claimed
CN-117881432-A Porphyrin-hydrogen porphyrin compounds, compositions comprising the same, and methods of use thereof 北卡罗莱纳州立大学 2024-04-12 CN disclosed
CN-117844431-A Thermoplastic polyurethane adhesive, preparation method and application thereof 万华化学集团股份有限公司 2024-04-09 CN disclosed
EP-4319823-A1 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF North Carolina State University (US) 2024-02-14 EP disclosed
WO-2022216927-A9 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF NORTH CAROLINA STATE UNIVERSITY (US) 2023-09-14 WO disclosed
CN-114316197-B Thermoplastic polyurethane adhesive with low polarity and high heat resistance and application thereof 万华化学集团股份有限公司 2023-07-14 CN disclosed
US-20070027311-A1 Methods and intermediates for the synthesis of porphyrins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed
US-20070027312-A1 Methods and intermediates for the synthesis of porphyrins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed
US-20060194960-A1 infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-08-31 US disclosed
US-5885968-A FOR HYPOLIPIDEMIC MEDICINES RIJKSUNIVERSITEIT TE LEIDEN (NL) 1999-03-23 US disclosed
EP-0655070-B1 TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE UNIV LEIDEN (NL) 1998-07-22 EP disclosed
US-5707989-A ANTITUMOR AGENTS, INHIBITING SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES DR. KARL THOMAE GMBH (DE) 1998-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060194960-A1 infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices PCNA, SCD, BCL6 ALDH1A1 205/4885LMNA 2225/4885TSHR 4693/4885
US-20070027312-A1 Methods and intermediates for the synthesis of porphyrins PPOX, DHPS, POR ALDH1A1 567/4885LMNA 1601/4885TSHR 3840/4885
US-20100016349-A1 PSEUDOAZULENYL NITRONES TXN2, NOX5, TXNRD2 ALDH1A1 900/4885LMNA 652/4885TSHR 3186/4885
US-20070027311-A1 Methods and intermediates for the synthesis of porphyrins PPOX, HMBS, CYC1 ALDH1A1 917/4885LMNA 1169/4885TSHR 4480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.