Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 19/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776461 | 0.81 | TDO2 (0.42) | FEN1ALOX5APTDO2 | |
| SCHEMBL5776718 | 0.81 | TDO2 (0.42) | FEN1ALOX5APTDO2 | |
| SCHEMBL5775480 | 0.81 | TDO2 (0.42) | FEN1ALOX5APTDO2 | |
| SCHEMBL28284231 | 0.79 | TDO2 (0.40) | FEN1ALOX5APTDO2 | |
| SCHEMBL2718434 | 0.74 | CYP11B2 (0.43) | FEN1ALOX5APTDO2 | |
| SCHEMBL27952428 | 0.74 | CEL (0.44) | FEN1ALOX5APTDO2 | |
| SCHEMBL5954915 | 0.72 | NOS1 (0.42) | FEN1ALOX5APTDO2 | |
| SCHEMBL29526095 | 0.71 | NOS3 (0.45) | FEN1ALOX5APTDO2 | |
| SCHEMBL928999 | 0.71 | NOS3 (0.45) | FEN1ALOX5APTDO2 | |
| SCHEMBL19723920 | 0.70 | TDO2 (0.42) | FEN1ALOX5APTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018030-B2 | Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | VALO HEALTH, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20210332052-A1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH, INC. | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018030-B2 | Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | USP7, UBA7, UBXN1 | FEN1 976/4885ALOX5AP 2107/4885TDO2 2006/4885 |
| US-20210332052-A1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | USP7, UBA7, UBXN1 | FEN1 976/4885ALOX5AP 2107/4885TDO2 2006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.