Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EIF2AK4 | Q9P2K8 | 6/20 | 0.35 |
| ▸ | LPL | P06858 | 4/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.35 |
| ▸ | CASP3 | P42574 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25322090 | 0.88 | PIK3CA (0.38) | NR1H4NPC1RAB9ASMN1; SMN2LPL | |
| SCHEMBL25812124 | 0.82 | NR1H4 (0.57) | NR1H4NPC1RAB9ASMN1; SMN2EIF2AK4 | |
| SCHEMBL23977681 | 0.80 | AHR (0.47) | NR1H4NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL23977685 | 0.73 | TSHR (0.55) | NPC1SMN1; SMN2 | |
| SCHEMBL23977683 | 0.73 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL25316312 | 0.72 | LPL (0.37) | NPC1RAB9ASMN1; SMN2LPLLIPG | |
| SCHEMBL24369182 | 0.71 | POLB (0.44) | EIF2AK4FLT3POLB | |
| SCHEMBL19243772 | 0.71 | FLT3 (0.40) | LPLLIPGFLT3 | |
| SCHEMBL312801 | 0.70 | FLT3 (0.44) | NR1H4NPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL31084022 | 0.69 | LPL (0.53) | NPC1RAB9ASMN1; SMN2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101045-A1 | SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES | LONG ISLAND UNIV (US) | 2025-03-27 | — | — | US | disclosed |
| EP-4466275-A2 | SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES | Long Island University (US) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023141114-A2 | SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES | LONG ISLAND UNIVERSITY (US) | 2023-07-27 | — | — | WO | disclosed |
| WO-2023141114-A2 | SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES | LONG ISLAND UNIVERSITY (US) | 2023-07-27 | — | — | WO | disclosed |
| US-20230219893-A1 | Krüppel-Like Factor 15 (KLF15) Small Molecule Agonists in Kidney Disease | US GOV VETERANS AFFAIRS (US) | 2023-07-13 | — | — | US | disclosed |
| US-20230219893-A1 | Krüppel-Like Factor 15 (KLF15) Small Molecule Agonists in Kidney Disease | US GOV VETERANS AFFAIRS (US) | 2023-07-13 | — | — | US | disclosed |
| US-11643394-B2 | Krüppel-like factor 15 (KLF15) small molecule agonists in kidney disease | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-05-09 | — | — | US | disclosed |
| US-11643394-B2 | Krüppel-like factor 15 (KLF15) small molecule agonists in kidney disease | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-05-09 | — | — | US | disclosed |
| US-20210347734-A1 | Krüppel-Like Factor 15 (KLF15) Small Molecule Agonists in Kidney Disease | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2021-11-11 | — | — | US | disclosed |
| WO-2021222637-A1 | KRÜPPEL-LIKE FACTOR 15 (KLF15) SMALL MOLECULE AGONISTS IN KIDNEY DISEASE | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11643394-B2 | Krüppel-like factor 15 (KLF15) small molecule agonists in kidney disease | KIF15, KLF5, KLF10 | NR1H4 1765/4885NPC1 834/4885RAB9A 1697/4885 |
| US-20230219893-A1 | Krüppel-Like Factor 15 (KLF15) Small Molecule Agonists in Kidney Disease | KIF15, KLF5, KLF10 | NR1H4 1765/4885NPC1 834/4885RAB9A 1697/4885 |
| US-20210347734-A1 | Krüppel-Like Factor 15 (KLF15) Small Molecule Agonists in Kidney Disease | KIF15, KLF5, KLF10 | NR1H4 1765/4885NPC1 834/4885RAB9A 1697/4885 |
| US-20250101045-A1 | SYNTHESIS OF BORON-CONTAINING AMIDOXIME REAGENTS AND THEIR APPLICATION TO SYNTHESIZE FUNCTIONALIZED OXADIAZOLE AND QUINAZOLINONE DERIVATIVES | PADI3, PADI2, PADI1 | NR1H4 2495/4885NPC1 3763/4885RAB9A 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.