SCHEMBL240964

SCHEMBL240964

O=C(Nc1cc(Cl)c(Cl)c(Cl)c1)c1ccccc1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 1/20 0.65
LMNA P02545 4/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
TP53 P04637 3/20 0.64
HTT P42858 3/20 0.64
HSD17B10 Q99714 2/20 0.64
KDM4E B2RXH2 1/20 0.64
HPGD P15428 1/20 0.64
PNLIP P16233 3/20 0.60
P2RX1 P51575 2/20 0.59
P2RX4 Q99571 1/20 0.59
P2RX7 Q99572 1/20 0.59
DHODH Q02127 1/20 0.59
NPC1 O15118 3/20 0.58
RAB9A P51151 2/20 0.58
POLB P06746 2/20 0.57
NFKB1 P19838 1/20 0.57
NFKB2 Q00653 1/20 0.57
RELA Q04206 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601056 1.00 FADS1 (0.65) FADS1LMNAMEN1KMT2ATP53
SCHEMBL11594877 0.90 DHODH (0.72) FADS1LMNAMEN1KMT2ATP53
SCHEMBL11789939 0.87 FADS1 (0.61) FADS1LMNAMEN1KMT2ATP53
SCHEMBL28093056 0.85 PTGS1 (0.72) FADS1LMNAMEN1KMT2ATP53
SCHEMBL11786428 0.85 FADS1 (0.68) FADS1LMNAMEN1KMT2ATP53
SCHEMBL330755 0.85 FADS1 (0.77) FADS1LMNAMEN1KMT2ATP53
Triclocarban SCHEMBL20898542 0.84 MEN1 (0.62) FADS1LMNAMEN1KMT2AHTT
SCHEMBL11793144 0.83 MEN1 (0.59) FADS1LMNAMEN1KMT2ATP53
SCHEMBL11789827 0.83 DHODH (0.72) FADS1LMNAMEN1KMT2ATP53
SCHEMBL11789286 0.83 PNLIP (0.57) FADS1LMNAMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024127414-A1 A COSMETIC COMPOSITION FOR ACNE CONTROL AND METHODS THEREOF L'OREAL (FR) 2024-06-20 WO claimed
US-20230218641-A1 ANTI-ACNE COMPOSITIONS L'OREAL (FR) 2023-07-13 US claimed
EP-4153127-A1 ANTI-ACNE COMPOSITIONS L'OREAL (FR) 2023-03-29 EP claimed
WO-2021234014-A1 ANTI-ACNE COMPOSITIONS L'OREAL (FR) 2021-11-25 WO claimed
US-10555878-B2 Solid antiperspirant and/or deodorant composition in the form of a water-in-oil emulsion based on silicone emulsifiers and on waxes; method for treating body odours L'OREAL (FR) 2020-02-11 US claimed
WO-2018122014-A1 SUPERHYDROPHOBIC COSMETIC COMPOSITION IN AEROSOL FORM L'OREAL (FR) 2018-07-05 WO claimed
US-20140193471-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'OREAL (FR) 2014-07-10 US claimed
US-20110212144-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'OREAL (FR) 2011-09-01 US claimed
EP-1586304-B2 Water in oil emulsion type deodorant cosmetic composition containing a polyolelfin derivative comprising at least one polar part as emulsifier OREAL (FR) 2011-08-17 EP claimed
EP-1550435-B1 Deodorizing oil-in-water emulsion comprising a mixture of alkylpolyglycoside and fatty alcohol and a non ionic associative polyether polyurethane OREAL (FR) 2008-10-22 EP claimed
US-20050019288-A1 Alcohol-based aerosol deodorant composition comprising at lease one zinc salicylate or a derivative thereof L'OREAL S.A. (FR) 2005-01-27 US claimed
EP-1486199-A1 Alcoholic aerosol deodorant composition containing zinc salicylate or a derivative thereof L'OREAL (FR) 2004-12-15 EP claimed
EP-1071324-B1 BLOOMING TYPE GERMICIDAL HARD-SURFACE CLEANERS RECKITT BENCKISER INC (US) 2004-02-11 EP claimed
WO-2003002081-A1 COMPOSITION COMPRISING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002078-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002080-A1 COMPOSITIONS CONTAINING A DERIVATIVE OF HYDROXYDIPHENYL ETHER INHIBITING THE DEVELOPMENT OF BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002079-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'OREAL (FR) 2003-01-09 WO claimed
WO-2003002072-A1 COMPOSITIONS CONTAINING A HYDROXYDIPHENYL ETHER DERIVATIVE INHIBITING BODY ODOURS L'ORÉAL (FR) 2003-01-09 WO claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140193471-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS DGAT1, DGAT2, DDT FADS1 682/4885LMNA 3709/4885MEN1 4326/4885
US-20230218641-A1 ANTI-ACNE COMPOSITIONS CUTA, EBP, ACMSD FADS1 150/4885LMNA 2543/4885MEN1 4638/4885
US-20110212144-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS DGAT1, DGAT2, DDT FADS1 682/4885LMNA 3709/4885MEN1 4326/4885
US-20050019288-A1 Alcohol-based aerosol deodorant composition comprising at lease one zinc salicylate or a derivative thereof ADH5, ADH1A, ADH1C FADS1 443/4885LMNA 2839/4885MEN1 4140/4885
US-10555878-B2 Solid antiperspirant and/or deodorant composition in the form of a water-in-oil emulsion based on silicone emulsifiers and on waxes; method for treating body odours DGAT1, DGAT2, DDT FADS1 682/4885LMNA 3709/4885MEN1 4326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.