SCHEMBL24142137

SCHEMBL24142137

COC(=O)[C@@H]1CC[C@@H](N(OCc2ccccc2)S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CN1S(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.46
MMP1 P03956 2/20 0.43
ADAM17 P78536 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
MAPK1 P28482 1/20 0.42
ANPEP P15144 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ATM Q13315 1/20 0.40
HSP90AA1 P07900 1/20 0.39
KMT2A Q03164 1/20 0.39
MMP3 P08254 1/20 0.39
CCR5 P51681 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23668286 0.91 MMP1 (0.43) MMP2MMP1ADAM17TDP1MAPK1
SCHEMBL24142140 0.89 MAPK1 (0.43) MMP2TDP1MAPK1ANPEPMAPT
SCHEMBL28577303 0.89 MMP2 (0.46) MMP2TDP1MAPK1ANPEPMAPT
SCHEMBL24142105 0.89 MAPK1 (0.43) MMP2TDP1MAPK1ANPEPMAPT
SCHEMBL30695875 0.86 MAPK1 (0.41) MMP2TDP1MAPK1ANPEPMAPT
SCHEMBL30695869 0.85 CCR5 (0.42) MMP2MMP1TDP1MAPK1ALDH1A1
SCHEMBL23668284 0.82 MAPK1 (0.43) MMP2TDP1MAPK1ANPEPALDH1A1
SCHEMBL18674017 0.81 STS (0.41) MMP2MMP1ADAM17MAPTALDH1A1
SCHEMBL24141866 0.80 MAPK1 (0.45) TDP1MAPK1MAPTALDH1A1L3MBTL1
SCHEMBL23668279 0.79 CCR5 (0.43) TDP1MAPK1ALDH1A1ATMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854786-B1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES UBE CORP (JP) 2026-02-18 EP disclosed
US-12281074-B2 Method for producing amino acid derivatives UBE CORPORATION (JP) 2025-04-22 US disclosed
US-12202800-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2025-01-21 US disclosed
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-05-09 US disclosed
US-11897844-B2 Method for producing amino acid derivatives API CORPORATION (JP) 2024-02-13 US disclosed
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2024-01-04 US disclosed
US-20210403427-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES API CORPORATION (JP) 2021-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210403427-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGES2 MMP2 3155/4885MMP1 2921/4885ADAM17 4383/4885
US-20240150292-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES PTGS2, PTGES, PTGS1 MMP2 3356/4885MMP1 3031/4885ADAM17 4395/4885
US-12202800-B2 Method for producing amino acid derivatives GLO1, BCAT2, BCAT1 MMP2 2853/4885MMP1 1277/4885ADAM17 3546/4885
US-20240002340-A1 METHOD FOR PRODUCING AMINO ACID DERIVATIVES GLO1, BCAT2, BCAT1 MMP2 2853/4885MMP1 1277/4885ADAM17 3546/4885
US-11897844-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 MMP2 3155/4885MMP1 2921/4885ADAM17 4383/4885
US-12281074-B2 Method for producing amino acid derivatives PTGS2, PTGES, PTGES2 MMP2 3155/4885MMP1 2921/4885ADAM17 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.