SCHEMBL242548

SCHEMBL242548

O=P(O)(O)CC(CP(=O)(O)O)CP(=O)(O)O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.48
GABBR1 Q9UBS5 1/20 0.48
KDM4E B2RXH2 1/20 0.44
MMP2 P08253 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
FOLH1 Q04609 9/20 0.42
TYMS P04818 1/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.39
ANPEP P15144 1/20 0.38
ERAP2 Q6P179 1/20 0.38
LAP3 P28838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21523050 0.83 GABBR2 (0.42) GABBR2GABBR1KDM4EMMP2THRB
SCHEMBL22973720 0.81 GABBR2 (0.40) GABBR2GABBR1KDM4EMMP2THRB
SCHEMBL7961190 0.81 LAP3 (0.48) GABBR2GABBR1MMP2FOLH1LAP3
SCHEMBL19211977 0.78 ENPEP (0.44) GABBR2GABBR1FOLH1TYMSNAALAD2
SCHEMBL19212140 0.78 ENPEP (0.44) GABBR2GABBR1FOLH1TYMSNAALAD2
SCHEMBL27495619 0.76 FOLH1 (0.60) GABBR2GABBR1FOLH1NAALAD2
SCHEMBL19212063 0.74 TYMS (0.52) GABBR2GABBR1FOLH1TYMS
SCHEMBL14727506 0.74 GABBR2 (0.36) GABBR2GABBR1KDM4EMMP2THRB
SCHEMBL19212086 0.74 ANPEP (0.39) GABBR2GABBR1FOLH1ANPEPLAP3
SCHEMBL781579 0.74 GABBR2 (0.41) GABBR2GABBR1KDM4EMMP2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP claimed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN claimed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US claimed
US-20190038802-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2019-02-07 US claimed
EP-3413934-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS Nano Bridging Molecules SA (CH) 2018-12-19 EP claimed
WO-2017137623-A1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2017-08-17 WO claimed
US-8173630-B2 Multipodal tethers for high-density attachment of redox-active moieties to substrates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-05-08 US claimed
EP-4319823-A1 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF North Carolina State University (US) 2024-02-14 EP disclosed
WO-2022216927-A9 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF NORTH CAROLINA STATE UNIVERSITY (US) 2023-09-14 WO disclosed
EP-3413934-B1 IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS NANO BRIDGING MOLECULES SA (CH) 2021-10-13 EP disclosed
CN-109195641-B Improved implant treatment with phosphonic acid compounds 纳米桥接分子股份公司 2021-07-27 CN disclosed
US-11000627-B2 Treatment of implants with phosphonic acid compounds NANO BRIDGING MOLECULES SA (CH) 2021-05-11 US disclosed
US-10919904-B2 Northern-southern route to synthesis of bacteriochlorins NORTH CAROLINA STATE UNIVERSITY (US) 2021-02-16 US disclosed
US-20070108438-A1 Multypodal tethers for high-density attachment of redox-active moieties to substrates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2007-05-17 US disclosed
WO-2007053192-A2 MULTIPODAL TETHERS FOR HIGH-DENSITY ATTACHMENT OF REDOX-ACTIVE MOIETIES TO SUBSTRATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-05-10 WO disclosed
WO-2007047925-A2 SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS NORTH CAROLINA STATE UNIVERSITY (US) 2007-04-26 WO disclosed
WO-2007018807-A2 METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF PORPHYRINS NORTH CAROLINA STATE UNIVERSITY (US) 2007-02-15 WO disclosed
US-20070027311-A1 Methods and intermediates for the synthesis of porphyrins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed
US-20070027312-A1 Methods and intermediates for the synthesis of porphyrins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-02-01 US disclosed
US-20060194960-A1 infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060194960-A1 infections, burns, sepsis, ulcers, periodontal disease, atherosclerosis, cosmetic and dermatologic conditions, acne, tissue sealing, neoplastic disease or cancer; active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, molecular memory devices PCNA, SCD, BCL6 GABBR2 3223/4885GABBR1 3432/4885KDM4E 4311/4885
US-10919904-B2 Northern-southern route to synthesis of bacteriochlorins DLD, HCCS, PPIF GABBR2 2092/4885GABBR1 2021/4885KDM4E 4549/4885
US-20070027312-A1 Methods and intermediates for the synthesis of porphyrins PPOX, DHPS, POR GABBR2 2302/4885GABBR1 2668/4885KDM4E 3569/4885
US-20070027311-A1 Methods and intermediates for the synthesis of porphyrins PPOX, HMBS, CYC1 GABBR2 2691/4885GABBR1 2854/4885KDM4E 3462/4885
US-20070108438-A1 Multypodal tethers for high-density attachment of redox-active moieties to substrates DNMT1, TET1, SOD1 GABBR2 2305/4885GABBR1 1886/4885KDM4E 901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.