Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL761109 | 0.94 | EDNRA (0.47) | CA1CA2CES2CES1EDNRA | |
| Trifluoroacetic Acid SCHEMBL1834215 | 0.85 | KMT2A (0.46) | RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL318069 | 0.80 | CA1 (0.38) | CA1CA2 | |
| Toliodium SCHEMBL10907987 | 0.79 | CA2 (0.40) | CA1CA2CES2CES1CA9 | |
| Trifluoroacetic Acid SCHEMBL10492085 | 0.79 | HDAC1 (0.46) | PDK1PDK2PDK3PDK4PARP10 | |
| Acetic Acid SCHEMBL9794942 | 0.79 | CES2 (0.50) | CA1CA2CES2CES1TAS1R3 | |
| Trifluoromethanesulfonic Acid SCHEMBL1592826 | 0.79 | PKM (0.47) | CA1CA2HSD11B1CA12CA7 | |
| SCHEMBL144129 | 0.78 | CA1 (0.65) | CA1CA2CES2CES1CA12 | |
| Trifluoroacetic Acid SCHEMBL10584037 | 0.77 | LTA4H (0.44) | PARP10NPC1RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3167314 | 0.77 | NQO2 (0.40) | EDNRARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3284736-B1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3284736-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NUtech Ventures (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2537826-B1 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9302990-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2016-04-05 | — | — | US | disclosed |
| EP-2726446-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | Nutech Ventures (US) | 2014-05-07 | — | — | EP | disclosed |
| US-8604213-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2013-12-10 | — | — | US | disclosed |
| US-8377704-B2 | Detection and quantification of anions | NUTECH VENTURES (US) | 2013-02-19 | — | — | US | disclosed |
| WO-2013003734-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | NUTECH VENTURES (US) | 2013-01-03 | — | — | WO | disclosed |
| EP-2537826-A1 | Fluorination of aromatic ring systems | Nutech Ventures (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2012-01-05 | — | — | US | disclosed |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-12-22 | — | — | US | disclosed |
| EP-2349977-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | The Board of Regents of the University of Nebraska (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20110091982-A1 | Detection and Quantification of Anions | NUTECH VENTURES | 2011-04-21 | — | — | US | disclosed |
| WO-2010048170-A2 | FLUORINATION OF AROMATIC RING SYSTEMS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | PFAS, SLC43A1, DDC | CA1 3898/4885CA2 3635/4885CES2 1207/4885 |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | PFAS, SLC43A1, DDC | CA1 3898/4885CA2 3635/4885CES2 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.