SCHEMBL24376040

SCHEMBL24376040

CCOC(=O)c1c(C)ncn1CC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 3/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPK1 P28482 3/20 0.44
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
MAPT P10636 3/20 0.41
GAA P10253 1/20 0.41
RECQL P46063 1/20 0.41
MAPK10 P53779 1/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
HCRTR1 O43613 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31332883 0.85 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL28558147 0.85 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL28567653 0.83 LMNA (0.45) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL31332941 0.83 KDM4E (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL28565106 0.83 SMN1; SMN2 (0.42) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL19798047 0.83 KMT2A (0.42) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL19797891 0.83 TGFBR1 (0.47) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL20360622 0.82 LMNA (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL4125342 0.82 TNF (0.40) ALDH1A1KDM4EHPGDHSD17B10MAPK1
SCHEMBL31332978 0.81 KDM4E (0.52) ALDH1A1KDM4EHPGDHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479834-B2 Phenol compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO. LTD. (JP) 2023-02-16 US disclosed
US-20230002360-A1 Heterocycloalkyl compounds as CCR2 / CCR5 antagonists Wuxi Life Fountain Biotech Co., Ltd. (CN) 2023-01-05 US disclosed
EP-4067343-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF Taiho Pharmaceutical Co., Ltd. (JP) 2022-10-05 EP disclosed
EP-3988098-A1 HETEROCYCLO ALKYL COMPOUNDS USED AS CCR2/CCR5 ANTAGONIST Shenzhen Lingfang Biotech Co., Ltd (CN) 2022-04-27 EP disclosed
WO-2021106230-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF 大鵬薬品工業株式会社 2021-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002360-A1 Heterocycloalkyl compounds as CCR2 / CCR5 antagonists CCR2, CCR5, CCRL2 ALDH1A1 1967/4885KDM4E 4505/4885HPGD 1037/4885
US-12479834-B2 Phenol compound or salt thereof REN, MLX, MYB ALDH1A1 287/4885KDM4E 696/4885HPGD 4260/4885
US-20230049402-A1 NOVEL PHENOL COMPOUND OR SALT THEREOF MYB, MLX, EP300 ALDH1A1 235/4885KDM4E 570/4885HPGD 4347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.