Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.47 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.35 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043300 | 0.84 | RECQL (0.39) | CA2RECQLCA4 | |
| Sulfuric Acid SCHEMBL28988908 | 0.83 | RECQL (0.52) | CA2RECQLTSHRALDH1A1 | |
| SCHEMBL8507473 | 0.81 | RECQL (0.43) | RECQLTSHRALDH1A1 | |
| SCHEMBL790709 | 0.81 | RECQL (0.58) | RECQLTSHRALDH1A1 | |
| SCHEMBL6902358 | 0.81 | CA2 (0.40) | CA2RECQLTSHRCA1ALDH1A1 | |
| SCHEMBL28910564 | 0.81 | RECQL (0.47) | RECQLTSHRALDH1A1 | |
| SCHEMBL9777495 | 0.80 | CA2 (0.41) | CA2RECQLCA1 | |
| SCHEMBL472038 | 0.80 | RECQL (0.56) | RECQLTSHRALDH1A1 | |
| SCHEMBL22528173 | 0.80 | RECQL (0.56) | RECQLTSHRALDH1A1 | |
| SCHEMBL30579947 | 0.80 | RECQL (0.56) | RECQLTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905878-B1 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | WACKER CHEMICAL CORP (US) | 2011-09-14 | — | — | EP | claimed |
| US-7485590-B2 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | WACKER CHEMICAL CORPORATION | 2009-02-03 | — | — | US | claimed |
| US-20080081530-A1 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | WACKER POLYMERS, L.P. | 2008-04-03 | — | — | US | claimed |
| EP-1905878-A2 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | AIR PRODUCTS POLYMERS, L.P. (US) | 2008-04-02 | — | — | EP | claimed |
| EP-1905878-B1 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | WACKER CHEMICAL CORP (US) | 2011-09-14 | — | — | EP | disclosed |
| US-20090118147-A1 | LOW VOLATILE ORGANIC CONTENT LUBRICANT | TEXAS RESEARCH INTERNATIONAL, INC. | 2009-05-07 | — | — | US | disclosed |
| US-7524797-B1 | Low volatile organic content lubricant | TEXAS RESEARCH INTERNATIONAL, INC. (US) | 2009-04-28 | — | — | US | disclosed |
| US-7485590-B2 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | WACKER CHEMICAL CORPORATION | 2009-02-03 | — | — | US | disclosed |
| US-20080081530-A1 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | WACKER POLYMERS, L.P. | 2008-04-03 | — | — | US | disclosed |
| EP-1905878-A2 | Self-crosslinking vinyl acetate-ethylene polymeric binders for nonwoven webs | AIR PRODUCTS POLYMERS, L.P. (US) | 2008-04-02 | — | — | EP | disclosed |
| EP-0431112-B1 | HIGH STRENGTH STRUCTURAL PERLITE CONCRETE | ADVANCED CONCRETE TECH (US) | 1994-08-17 | — | — | EP | disclosed |
| US-5114617-A | Cement, pozzolan, fine and coarse aggregates; bonding strength | ADVANCED CONCRETE TECHNOLOGY, INC. (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0431112-A4 | HIGH STRENGTH STRUCTURAL PERLITE CONCRETE | — | 1991-11-27 | — | — | EP | disclosed |
| EP-0431112-A1 | HIGH STRENGTH STRUCTURAL PERLITE CONCRETE. | ADVANCED CONCRETE TECH (US) | 1991-06-12 | — | — | EP | disclosed |
| WO-1990014319-A1 | HIGH STRENGTH STRUCTURAL PERLITE CONCRETE | ADVANCED CONCRETE TECHNOLOGY, INC. (US) | 1990-11-29 | — | — | WO | disclosed |