Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.40 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.34 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.34 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774149 | 0.85 | RECQL (0.41) | CA2RECQLCA4CA1CYP3A4 | |
| SCHEMBL27831782 | 0.84 | CA2 (0.36) | CA2RECQLCA4CYP3A4TSHR | |
| SCHEMBL11518722 | 0.84 | CA2 (0.36) | CA2ALDH1A1CA4CA12CA1 | |
| SCHEMBL28190321 | 0.82 | CA2 (0.41) | CA2RECQLCA4CA12CA1 | |
| SCHEMBL29272017 | 0.82 | RECQL (0.46) | CA2RECQLALDH1A1CA1TSHR | |
| SCHEMBL1498017 | 0.82 | RECQL (0.46) | CA2RECQLALDH1A1CA1TSHR | |
| Ether SCHEMBL18893637 | 0.81 | CA2 (0.38) | CA2RECQLCA4CYP3A4TSHR | |
| SCHEMBL2437684 | 0.81 | CA2 (0.47) | CA2RECQLALDH1A1CA4CA1 | |
| SCHEMBL9176900 | 0.81 | CA2 (0.38) | CA2RECQLCA4CYP3A4TSHR | |
| SCHEMBL6138906 | 0.81 | RECQL (0.44) | RECQLCA1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331001-B1 | NOVEL DISPERSIBLE AND SOLUBLE GALENIC PARACETAMOL FORMULATION, METHOD FOR ITS PREPARATION AND ITS APPLICATIONS | BELMAC S A LAB (ES) | 2004-07-21 | — | — | EP | claimed |
| US-6620433-B2 | Dispersible and soluble galenic paracetamol formulation, method for its preparation and its applications | LABORATORIOS BELMAC, S.A. (ES) | 2003-09-16 | — | — | US | claimed |
| EP-1331001-A1 | NOVEL DISPERSIBLE AND SOLUBLE GALENIC PARACETAMOL FORMULATION, METHOD FOR ITS PREPARATION AND ITS APPLICATIONS | Laboratorios Belmac, S.A. (ES) | 2003-07-30 | — | — | EP | claimed |
| US-20020197312-A1 | Dispersible and soluble galenic paracetamol formulation, method for its preparation and its applications | LABORATORIES BELMAC, S.A. (ES) | 2002-12-26 | — | — | US | claimed |
| CN-103748181-A | Branched polyalkylene glycol ethers as de-airing wetting and dispersing agents for aqueous dispersion colors | CLARIANT INT LTD | 2014-04-23 | — | — | CN | disclosed |
| CN-102762620-A | Polymers and use thereof as dispersants having a foam-inhibiting effect | CLARIANT FINANCE BVI LTD | 2012-10-31 | — | — | CN | disclosed |
| CN-1671475-A | Copolymers of alkylene oxides and glycidyl ethers and their use as polymerizable emulsifiers | CLARIANT GMBH (DE) | 2005-09-21 | — | — | CN | disclosed |
| EP-1331001-B1 | NOVEL DISPERSIBLE AND SOLUBLE GALENIC PARACETAMOL FORMULATION, METHOD FOR ITS PREPARATION AND ITS APPLICATIONS | BELMAC S A LAB (ES) | 2004-07-21 | — | — | EP | disclosed |
| US-6620433-B2 | Dispersible and soluble galenic paracetamol formulation, method for its preparation and its applications | LABORATORIOS BELMAC, S.A. (ES) | 2003-09-16 | — | — | US | disclosed |
| EP-1331001-A1 | NOVEL DISPERSIBLE AND SOLUBLE GALENIC PARACETAMOL FORMULATION, METHOD FOR ITS PREPARATION AND ITS APPLICATIONS | Laboratorios Belmac, S.A. (ES) | 2003-07-30 | — | — | EP | disclosed |
| US-20020197312-A1 | Dispersible and soluble galenic paracetamol formulation, method for its preparation and its applications | LABORATORIES BELMAC, S.A. (ES) | 2002-12-26 | — | — | US | disclosed |