SCHEMBL244032

SCHEMBL244032

COc1ccc(C(=NO)c2ccc(OC)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.68
ALDH1A1 P00352 2/20 0.68
KDM4E B2RXH2 2/20 0.55
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
CA1 P00915 5/20 0.52
CA2 P00918 5/20 0.52
CA12 O43570 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NR1I2 O75469 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
PARP1 P09874 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
MGLL Q99685 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875642 0.92 MGLL (0.60) SMN1; SMN2ALDH1A1KDM4ECES2CES1
SCHEMBL13838583 0.81 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1KDM4ECES2CES1
SCHEMBL10861214 0.81 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1KDM4ENR1I2MGLL
SCHEMBL27944058 0.79 ALDH1A1 (0.59) SMN1; SMN2ALDH1A1KDM4ECES2CES1
SCHEMBL18138463 0.79 CES2 (0.58) SMN1; SMN2ALDH1A1CES2CES1CA1
SCHEMBL5666851 0.79 SMN1; SMN2 (0.65) SMN1; SMN2ALDH1A1KDM4ECES2CES1
SCHEMBL30322657 0.79 SMN1; SMN2 (0.65) SMN1; SMN2ALDH1A1KDM4ECES2CES1
SCHEMBL24105688 0.77 ESR2 (0.61) SMN1; SMN2ALDH1A1CES2CES1CA1
SCHEMBL103228 0.77 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1KDM4ECA1CA2
SCHEMBL3551617 0.77 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1KDM4ECES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552959-B2 Aqueous coating composition for corrosion protection ALLNEX AUSTRIA GMBH (AT) 2026-02-17 US disclosed
US-20250160331-A1 ANTIBACTERIAL AGENT MITSUI CHEMICALS, INC. (JP) 2025-05-22 US disclosed
WO-2025070528-A1 ANTIVIRAL AGENT 三井化学株式会社 2025-04-03 WO disclosed
WO-2025070529-A1 ANTIFUNGAL AGENT 三井化学株式会社 2025-04-03 WO disclosed
EP-4501113-A1 ANTIBACTERIAL AGENT Mitsui Chemicals, Inc. (JP) 2025-02-05 EP disclosed
US-12134714-B2 Thermosetting adhesive and adhesive sheet NITTO SHINKO CORPORATION (JP) 2024-11-05 US disclosed
US-12115791-B2 Ink jet recording apparatus and maintenance method SEIKO EPSON CORPORATION 2024-10-15 US disclosed
US-20240084167-A1 AQUEOUS COATING COMPOSITION FOR CORROSION PROTECTION ALLNEX AUSTRIA GMBH (AT) 2024-03-14 US disclosed
EP-4330335-A1 AQUEOUS COATING COMPOSITION FOR CORROSION PROTECTION Allnex Austria GmbH (AT) 2024-03-06 EP disclosed
EP-3702421-B1 INK-JET INK COMPOSITION AND INK JET RECORDING METHOD SEIKO EPSON CORP (JP) 2023-10-18 EP disclosed
EP-0479332-A2 Diphenyl-methane derivative, pharmaceutical composition and use Eisai Co., Ltd. (JP) 1992-04-08 EP disclosed
US-5103010-A DIPHENYLETHYLENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND TREATMENT METHOD EISAI CO., LTD. (JP) 1992-04-07 US disclosed
EP-0478001-A1 Benzophenone oxime derivatives, pharmaceutical compositions and use Eisai Co., Ltd. (JP) 1992-04-01 EP disclosed
US-5064848-A Anticoagulants EISAI CO., LTD. (JP) 1991-11-12 US disclosed
US-5034418-A Anticoagulants EISAI CO., LTD. (JP) 1991-07-23 US disclosed
US-4978767-A ANTICOAGULANTS EISAI CO., LTD. (JP) 1990-12-18 US disclosed
US-4954523-A ANTICOAGULANT EISAI CO., LTD. (JP) 1990-09-04 US disclosed
EP-0346943-A1 Diphenyl-methane derivative, pharmaceutical composition and use Eisai Co., Ltd. (JP) 1989-12-20 EP disclosed
US-4886834-A ANTICOAGULANTS EISAI CO., LTD. (JP) 1989-12-12 US disclosed
US-4176194-A ANTIINFLAMMATORY AGENTS; ANALGESICS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552959-B2 Aqueous coating composition for corrosion protection ADH1A, ADH1C, TET1 SMN1; SMN2 2217/4885ALDH1A1 87/4885KDM4E 164/4885
US-20250160331-A1 ANTIBACTERIAL AGENT CAPG, ALKBH1, ALKBH5 SMN1; SMN2 4187/4885ALDH1A1 3601/4885KDM4E 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.