Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Solriamfetol SCHEMBL30929349 | 0.87 | PKM (0.56) | EPHX1MMP2ALPIPKMPTGS1 | |
| Solriamfetol SCHEMBL42525 | 0.87 | PKM (0.56) | EPHX1MMP2ALPIPKMPTGS1 | |
| Solriamfetol SCHEMBL30929348 | 0.87 | PKM (0.56) | EPHX1MMP2ALPIPKMPTGS1 | |
| Solriamfetol SCHEMBL42526 | 0.87 | PKM (0.56) | EPHX1MMP2ALPIPKMPTGS1 | |
| Solriamfetol SCHEMBL2739637 | 0.87 | PKM (0.56) | EPHX1MMP2ALPIPKMPTGS1 | |
| Solriamfetol SCHEMBL28413501 | 0.86 | PKM (0.54) | EPHX1MMP2ALPIPKMPTGS1 | |
| Solriamfetol SCHEMBL8430382 | 0.86 | PKM (0.54) | EPHX1MMP2ALPIPKMPTGS1 | |
| SCHEMBL28168081 | 0.86 | MMP2 (0.55) | EPHX1MMP2ALPIPKMPTGS1 | |
| Solriamfetol SCHEMBL4987496 | 0.86 | PKM (0.54) | EPHX1MMP2ALPIPKMPTGS1 | |
| SCHEMBL12691524 | 0.86 | ALDH1A1 (0.55) | EPHX1MMP2ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | ALIVUS LIFE SCIENCES LIMITED (IN) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | TST, SPR, STS | EPHX1 2179/4885MMP2 2387/4885ALPI 3058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.