SCHEMBL2450835

SCHEMBL2450835

c1ccc(-c2ccc3c4cccc5cccc(c6ccc(-c7ccccc7)c2c36)c54)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HPGD P15428 5/20 0.48
HSD17B10 Q99714 5/20 0.48
CYP1A2 P05177 2/20 0.48
THRB P10828 1/20 0.48
ERBB2 P04626 1/20 0.44
FYN P06241 1/20 0.44
MAOA P21397 1/20 0.44
ACHE P22303 1/20 0.44
AHR P35869 1/20 0.44
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MPI P34949 1/20 0.41
CDK4 P11802 3/20 0.40
CCND1 P24385 3/20 0.40
L3MBTL1 Q9Y468 4/20 0.39
TSHR P16473 4/20 0.39
MAPK1 P28482 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444804 1.00 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL634392 0.88 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL29444799 0.87 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10MAPTMEN1
SCHEMBL2453452 0.87 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10MAPTMEN1
SCHEMBL5139143 0.86 ALDH1A1 (0.58) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL15672997 0.85 PARP1 (0.39) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL8365533 0.85 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL26726672 0.85 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL1231583 0.83 ALDH1A1 (0.61) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL29788646 0.83 ALDH1A1 (0.61) ALDH1A1HPGDHSD17B10CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5989737-A Organic electroluminescent devices XEROX CORPORATION (US) 1999-11-23 US claimed
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
CN-116987108-A Polycyclic aromatic compound, material for organic element, composition for forming light-emitting layer, organic electroluminescent element, and device 学校法人关西学院 2023-11-03 CN disclosed
CN-116997557-A Polycyclic aromatic compound and organic electroluminescent element 学校法人关西学院 2023-11-03 CN disclosed
CN-116888132-A Polycyclic aromatic compounds 学校法人关西学院 2023-10-13 CN disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
EP-1640430-B1 Luminescent material and organic electroluminescent device using the same JNC CORP (JP) 2011-09-21 EP disclosed
EP-2177586-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2010-04-21 EP disclosed
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
CN-100339524-C Method for producing heat-resistant crimped yarn TORAY DU PONT KK (JP) 2007-09-26 CN disclosed
US-20070212568-A1 Organic Electroluminescent Device CHISSO CORPORATION (JP) 2007-09-13 US disclosed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP disclosed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US disclosed
CN-1455831-A Method for producing heat-resisting crimped yarn TORAY DU PONT KK (JP) 2003-11-12 CN disclosed
US-5989737-A Organic electroluminescent devices XEROX CORPORATION (US) 1999-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC ALDH1A1 2787/4885HPGD 4738/4885HSD17B10 4348/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR ALDH1A1 2290/4885HPGD 1893/4885HSD17B10 1498/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 ALDH1A1 1152/4885HPGD 3290/4885HSD17B10 2487/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 ALDH1A1 3052/4885HPGD 4325/4885HSD17B10 3889/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 ALDH1A1 3052/4885HPGD 4325/4885HSD17B10 3889/4885
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same C1S, EPB41, EPB41L2 ALDH1A1 1227/4885HPGD 2934/4885HSD17B10 2775/4885
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 ALDH1A1 944/4885HPGD 3560/4885HSD17B10 1895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.