SCHEMBL2450872

SCHEMBL2450872

c1cnc2c(c1)cc(-c1cc(-c3cc4cccnc4c4ncccc34)cc(-c3cc4cccnc4c4ncccc34)c1)c1cccnc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.61
CCR1 P32246 5/20 0.61
CCR8 P51685 5/20 0.61
MAPT P10636 2/20 0.53
ALDH1A1 P00352 2/20 0.53
CCR5 P51681 3/20 0.52
KDM4E B2RXH2 3/20 0.52
HSP90AA1 P07900 2/20 0.52
LMNA P02545 2/20 0.52
GMNN O75496 1/20 0.52
TP53 P04637 1/20 0.52
MMP2 P08253 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52
MMP8 P22894 1/20 0.52
THPO P40225 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30555210 1.00 L3MBTL1 (0.61) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL29444844 1.00 L3MBTL1 (0.61) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL18806863 0.92 CCR1 (0.58) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL17899329 0.92 CCR1 (0.61) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL18695360 0.91 CCR1 (0.53) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL17899341 0.91 L3MBTL1 (0.56) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL17125611 0.90 CCR1 (0.59) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL12914331 0.90 L3MBTL1 (0.68) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL913533 0.89 CCR1 (0.58) L3MBTL1CCR1CCR8MAPTALDH1A1
SCHEMBL29441295 0.89 CCR1 (0.58) L3MBTL1CCR1CCR8MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
EP-3960744-B1 CYCLOALKANE-FUSED POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUND (JP) 2024-08-21 EP disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-11800785-B2 Material for organic device and organic electroluminescent device using the same KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-10-24 US disclosed
US-20230329105-A1 ORGANIC SEMICONDUCTOR DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-10-12 US disclosed
US-20230329105-A1 ORGANIC SEMICONDUCTOR DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-10-12 US disclosed
US-20230329105-A1 ORGANIC SEMICONDUCTOR DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-10-12 US disclosed
US-7547912-B2 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJIFILM CORPORATION (JP) 2009-06-16 US disclosed
US-7547912-B2 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJIFILM CORPORATION (JP) 2009-06-16 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
US-20070212568-A1 Organic Electroluminescent Device CHISSO CORPORATION (JP) 2007-09-13 US disclosed
US-20070044829-A1 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070044829-A1 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20060110622-A1 Organic electroluminescent device LG ELECTRONICS, INC. (KR) 2006-05-25 US disclosed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP disclosed
EP-1624501-A2 Organic electroluminescent device LG Electronics, Inc. (KR) 2006-02-08 EP disclosed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 L3MBTL1 1119/4885CCR1 59/4885CCR8 689/4885
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 L3MBTL1 563/4885CCR1 1160/4885CCR8 2160/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 L3MBTL1 2002/4885CCR1 4677/4885CCR8 2085/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 L3MBTL1 1199/4885CCR1 3574/4885CCR8 2326/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 L3MBTL1 1199/4885CCR1 3574/4885CCR8 2326/4885
US-11800785-B2 Material for organic device and organic electroluminescent device using the same RER1, LEF1, CHRM1 L3MBTL1 27/4885CCR1 255/4885CCR8 1880/4885
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same C1S, EPB41, EPB41L2 L3MBTL1 126/4885CCR1 1179/4885CCR8 2416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.