Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 9/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | RIPK3 | Q9Y572 | 3/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 5/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459657 | 0.87 | DYRK1A (0.55) | DYRK1ATGFBR1ALDH1A1HSD17B10FFAR1 | |
| SCHEMBL28048502 | 0.84 | ALDH1A1 (0.54) | DYRK1ARIPK2KDRTGFBR1EGFR | |
| SCHEMBL2461252 | 0.75 | ACVR1 (0.44) | DYRK1ARIPK2KDRTGFBR1EGFR | |
| SCHEMBL29478085 | 0.75 | RIPK2 (0.60) | DYRK1ARIPK2KDRTGFBR1EGFR | |
| SCHEMBL927048 | 0.75 | RIPK2 (0.60) | DYRK1ARIPK2KDRTGFBR1EGFR | |
| SCHEMBL1852870 | 0.74 | FFAR1 (0.48) | DYRK1ARIPK2KDRTGFBR1EGFR | |
| SCHEMBL6650934 | 0.74 | FFAR1 (0.48) | DYRK1ARIPK2KDRTGFBR1EGFR | |
| SCHEMBL13394464 | 0.74 | DYRK1A (0.51) | DYRK1ARIPK2KDRTGFBR1EGFR | |
| SCHEMBL2457772 | 0.73 | THRB (0.39) | ALDH1A1 | |
| SCHEMBL13394547 | 0.73 | NPC1 (0.50) | DYRK1ATGFBR1MAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | DYRK1A 4134/4885RIPK2 3574/4885KDR 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.