Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.56 |
| ▸ | FAAH | O00519 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516512 | 0.86 | MGLL (0.65) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL19514804 | 0.84 | MGLL (0.70) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL19514775 | 0.82 | MGLL (0.71) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL14957451 | 0.82 | MGLL (0.71) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL6771508 | 0.81 | MGLL (0.52) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL20780013 | 0.81 | MGLL (0.46) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL4859512 | 0.78 | MGLL (0.54) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL14678413 | 0.78 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL145737 | 0.78 | MGLL (0.77) | MGLLFAAHALDH1A1LMNAMAPT | |
| SCHEMBL24797680 | 0.78 | MGLL (0.74) | MGLLFAAHALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107921144-B | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-116726190-A | Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules | 杭州多禧生物科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116199747-A | Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | claimed |
| CN-116143678-A | Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-105189558-A | Combination therapy of afucosylated CD20 antibody with CD79b antibody-drug conjugate | HOFFMANN LA ROCHE | 2015-12-23 | — | — | CN | claimed |
| CN-105143268-A | Combination therapy of afucosylated CD20 antibody with CD22 antibody-drug conjugate | HOFFMANN LA ROCHE | 2015-12-09 | — | — | CN | claimed |
| CN-102471380-B | Anti-fcrh5 antibodies and immunoconjugates and methods of use | HOFFMANN LA ROCHE | 2015-01-14 | — | — | CN | claimed |
| CN-120082162-A | Flame-retardant modified ABS plastic and preparation method thereof | 东莞市精佰技术有限公司 | 2025-06-03 | — | — | CN | disclosed |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | SEAGEN INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | SEAGEN INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118215676-A | Specific conjugation of antibody drug conjugates | 杭州多禧生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117980327-A | Specific coupling of antibodies | 杭州多禧生物科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11827709-B2 | Anti-AVB6 antibodies and antibody-drug conjugates | SEAGEN INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20070128729-A1 | Method for the identification and relative quantification of proteins based on the selective isolation of RRnK peptides for the simplification of complex mixtures of proteins | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-06-07 | — | — | US | disclosed |
| US-20060234909-A1 | Compositions and methods for increasing drug efficiency | NEWMAN MICHAEL J | 2006-10-19 | — | — | US | disclosed |
| EP-1689439-A2 | SMALL MOLECULE COMPOSITIONS AND METHODS FOR INCREASING DRUG EFFICIENCY USING COMPOSITIONS THEREOF | Acidophil LLC (US) | 2006-08-16 | — | — | EP | disclosed |
| US-20050187147-A1 | Compositions and methods for increasing drug efficiency | ACIDOPHIL LLC | 2005-08-25 | — | — | US | disclosed |
| US-20050148534-A1 | Small molecule compositions and methods for increasing drug efficiency using compositions thereof | ACIDOPHIL LLC | 2005-07-07 | — | — | US | disclosed |
| WO-2005035003-A2 | COMPOSITIONS AND METHODS FOR INCREASING DRUG EFFICIENCY | DIHEDRON CORPORATION (US) | 2005-04-21 | — | — | WO | disclosed |
| WO-2005030258-A2 | SMALL MOLECULE COMPOSITIONS AND METHODS FOR INCREASING DRUG EFFICIENCY USING COMPOSITIONS THEREOF | ACIDOPHIL LLC (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827709-B2 | Anti-AVB6 antibodies and antibody-drug conjugates | ITGB6, ITGA6, ITGAV | MGLL 4848/4885FAAH 3698/4885ALDH1A1 1405/4885 |
| US-20060234909-A1 | Compositions and methods for increasing drug efficiency | ILK, DMPK, EPHA2 | MGLL 412/4885FAAH 2019/4885ALDH1A1 2458/4885 |
| US-20050187147-A1 | Compositions and methods for increasing drug efficiency | ILK, DMPK, EPHA2 | MGLL 412/4885FAAH 2019/4885ALDH1A1 2458/4885 |
| US-20050148534-A1 | Small molecule compositions and methods for increasing drug efficiency using compositions thereof | DMPK, PCK1, PHKG2 | MGLL 1209/4885FAAH 2901/4885ALDH1A1 1811/4885 |
| US-12036286-B2 | Selective drug release from internalized conjugates of biologically active compounds | CTSB, CTSE, CTSZ | MGLL 1865/4885FAAH 669/4885ALDH1A1 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.