Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 6/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786111 | 0.82 | PARP1 (0.38) | CDC7PLATPARP1IKBKBCHUK | |
| SCHEMBL4446215 | 0.73 | QDPR (0.48) | CDC7PLATPARP1IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL4435861 | 0.72 | QDPR (0.47) | CDC7PARP1IKBKBCHUKTLR9 | |
| SCHEMBL2466388 | 0.69 | SLC9A1 (0.37) | IKBKBCHUKSLC9A1 | |
| SCHEMBL4560312 | 0.66 | PARP1 (0.38) | CDC7PLATPARP1IKBKBCHUK | |
| SCHEMBL28325510 | 0.66 | PARP1 (0.57) | CDC7PARP1IKBKBCHUKPARP2 | |
| SCHEMBL8498415 | 0.64 | LMNA (0.37) | PARP1PARP2 | |
| SCHEMBL17786119 | 0.64 | IKBKB (0.47) | CDC7PLATPARP1IKBKBCHUK | |
| SCHEMBL6233771 | 0.63 | PARP1 (0.36) | CDC7PARP1IKBKBCHUKTLR8 | |
| SCHEMBL3809365 | 0.63 | PARP1 (0.51) | CDC7PARP1IKBKBCHUKPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012956-B2 | Tropane compounds | EXELIXIS, INC. (US) | 2011-09-06 | — | — | US | claimed |
| US-20090163471-A1 | Tropane compounds | EXELIXIS, INC. | 2009-06-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163471-A1 | Tropane compounds | ADRA1B, ADRA2B, ADRB2 | CDC7 4431/4885PLAT 1638/4885PARP1 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.