Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Terpin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.35 |
| ▸ | PTGS1 known ✓ | P23219 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terpin SCHEMBL29867 | 1.00 | TRPA1 (0.39) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| Terpin SCHEMBL5177695 | 0.98 | TRPA1 (0.38) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| Terpin SCHEMBL9536260 | 0.98 | TRPA1 (0.40) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| Terpin SCHEMBL19192 | 0.98 | TRPA1 (0.40) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| Terpin SCHEMBL5377815 | 0.98 | TRPA1 (0.40) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| Terpin SCHEMBL12506199 | 0.92 | PTGS1 (0.36) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| Terpin SCHEMBL5823396 | 0.87 | PTGS1 (0.39) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| SCHEMBL12384745 | 0.80 | ALDH1A1 (0.39) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| SCHEMBL10013221 | 0.80 | ALDH1A1 (0.39) | TRPA1ALDH1A1TDP1ESR2PTGS1 | |
| SCHEMBL13900364 | 0.80 | ALDH1A1 (0.39) | TRPA1ALDH1A1TDP1ESR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114513960-A | Antimicrobial composition for animal feed | 塔明克私人有限公司 | 2022-05-17 | — | — | CN | claimed |
| US-20240228416-A1 | TERPINEOL WITH CONTROLLED OPTICAL ROTATION FROM GUM TERPENTINE OIL AND PROCESS THEREOF | HIMACHAL TEREPENE PRODUCTS PVT. LTD. (IN) | 2024-07-11 | — | — | US | disclosed |
| EP-4330221-A1 | TERPINEOL WITH CONTROLLED OPTICAL ROTATION FROM GUM TERPENTINE OIL AND PROCESS THEREOF | Himachal Terepene Products Pvt. Ltd. (IN) | 2024-03-06 | — | — | EP | disclosed |
| CN-116457328-A | Aldehyde composition | 三菱瓦斯化学株式会社 | 2023-07-18 | — | — | CN | disclosed |
| CN-115427003-A | Granules comprising surface-reacted calcium carbonate as excipient | OMYA国际股份公司 | 2022-12-02 | — | — | CN | disclosed |
| WO-2022234590-A1 | TERPINEOL WITH CONTROLLED OPTICAL ROTATION FROM GUM TERPENTINE OIL AND PROCESS THEREOF | HIMACHAL TEREPENE PRODUCTS PVT. LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |
| CN-114513960-A | Antimicrobial composition for animal feed | 塔明克私人有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114502681-A | Mixed binder composition for shielding electromagnetic wave, method for preparing mixed binder for shielding electromagnetic wave, and mixed binder film for shielding electromagnetic wave | 贝斯特石墨烯株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-114272323-A | Traditional Chinese medicine formula for regulating and controlling intestinal function of lactating women | 华子昂 | 2022-04-05 | — | — | CN | disclosed |
| US-20140357806-A1 | THERMAL-RESPONSIVE POLYMER NETWORKS, COMPOSITIONS, AND METHODS AND APPLICATIONS RELATED THERETO | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2014-12-04 | — | — | US | disclosed |
| US-8597630-B2 | Thermal-responsive polymer networks, compositions, and methods and applications related thereto | UNIVERSITY OF MASSACHUSETTS (US) | 2013-12-03 | — | — | US | disclosed |
| WO-2011120002-A1 | THERMAL-RESPONSIVE POLYMER NETWORKS, COMPOSITIONS, AND METHODS AND APPLICATIONS RELATED THERETO | UNIVERSITY OF MASSACHUSETTS (US) | 2011-09-29 | — | — | WO | disclosed |
| US-20100280561-A1 | Thermal-Responsive Polymer Networks, Compositions, And Methods And Applications Related Thereto | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 2010-11-04 | — | — | US | disclosed |
| EP-0581274-A1 | Aroma-imparting method and aroma-emitting textile product | MATSUI SHIKISO CHEMICAL CO., LTD (JP) | 1994-02-02 | — | — | EP | disclosed |