Terpin

Terpin

SCHEMBL5377815

CC(C)(O)[C@H]1CC[C@@](C)(O)CC1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.40
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ESR2 Q92731 1/20 0.36
PTGS1 P23219 3/20 0.33
HSD11B1 P28845 1/20 0.33
LMNA P02545 1/20 0.33
CES2 O00748 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terpin SCHEMBL19192 1.00 TRPA1 (0.40) TRPA1ALDH1A1TDP1ESR2PTGS1
Terpin SCHEMBL9536260 1.00 TRPA1 (0.40) TRPA1ALDH1A1TDP1ESR2PTGS1
Terpin SCHEMBL29867 0.98 TRPA1 (0.39) TRPA1ALDH1A1TDP1ESR2PTGS1
Terpin SCHEMBL2487459 0.98 TRPA1 (0.39) TRPA1ALDH1A1TDP1ESR2PTGS1
Terpin SCHEMBL5177695 0.95 TRPA1 (0.38) TRPA1ALDH1A1TDP1ESR2PTGS1
Terpin SCHEMBL12506199 0.89 PTGS1 (0.36) TRPA1ALDH1A1TDP1ESR2PTGS1
Terpin SCHEMBL5823396 0.89 PTGS1 (0.39) TRPA1ALDH1A1TDP1ESR2PTGS1
SCHEMBL12384745 0.82 ALDH1A1 (0.39) TRPA1ALDH1A1TDP1ESR2PTGS1
SCHEMBL13900364 0.82 ALDH1A1 (0.39) TRPA1ALDH1A1TDP1ESR2PTGS1
SCHEMBL10013221 0.82 ALDH1A1 (0.39) TRPA1ALDH1A1TDP1ESR2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084046-B2 Incorporation of certain isoprenoid compounds into catamenial tampon to reduce or eliminate pathogenic microorganisms and menstrually occurring Toxic Shock Syndrome KIMBERLY-CLARK WORLDWIDE, INC. (US) 2011-12-27 US claimed
US-7294651-B2 Inhibition of exoprotein production using isoprenoid compositions KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-11-13 US claimed
US-6911480-B2 Methods for the inhibition of exoprotein production from Gram positive bacteria KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-06-28 US claimed
US-20050070604-A1 Inhibition of exoprotein production using isoprenoid compositions KIMBERLY-CLARK WORLDWIDE, INC. 2005-03-31 US claimed
EP-1432458-A1 INHIBITION OF EXOPROTEINS USING ISOPRENOIDS KIMBERLY-CLARK CORPORATION (US) 2004-06-30 EP claimed
US-20030165559-A1 Non-absorbent articles containing additives KIMBERLY-CLARK WORLDWIDE, INC. 2003-09-04 US claimed
US-20030161865-A1 Non-absorbent articles containing additives KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-28 US claimed
US-20030158156-A1 Methods for inhibiting the production of TSST-1 KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
US-20030158529-A1 Absorbent articles containing additives KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
US-20030157148-A1 Methods for inhibiting the production of TSST-1 KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
US-20030157149-A1 Menstrual tampons comprising cerulenin, triclosan, or hexachlorophene to inhibit production of toxic shock syndrome toxins by gram-positive bacteria KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
US-20030153629-A1 Methods for the inhibition of exoprotein production from Gram positive bacteria KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-14 US claimed
US-6596290-B2 Disposable product containing terpene; suppressing production of exotoxins by Gram positive bacteria KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-22 US claimed
US-20030105439-A1 Inhibition of exoprotein production in absorbent articles using isoprenoids KIMBERLY-CLARK WORLDWIDE, INC. 2003-06-05 US claimed
US-20030096877-A1 Inhibition of exoprotein production in non-absorbent articles using isoprenoid compositions KIMBERLY-CLARK WORLDWIDE, INC. 2003-05-22 US claimed
WO-2003028777-A1 INHIBITION OF EXOPROTEINS USING ISOPRENOIDS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-04-10 WO claimed
US-6534548-B1 Vaginal cleansers and douches; inhibit production of exotoxins from Grampositive bacteria KIMBERLY-CLARK WORLDWIDE, INC. 2003-03-18 US claimed
US-10590152-B2 Pinene-based flame retardant compounds INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-03-17 US disclosed
US-4831163-A REACTING TERPIN HYDRATE OR TERPINEOL WITH PHOSPHORIC ACID; DISTILLATION UNION CAMP CORPORATION (US) 1989-05-16 US disclosed
EP-0300117-A2 Method of preparing cineoles Union Camp Corporation (US) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153629-A1 Methods for the inhibition of exoprotein production from Gram positive bacteria MRPL21, ENGASE, FNTB TRPA1 4854/4885ALDH1A1 4820/4885TDP1 4407/4885
US-20030161865-A1 Non-absorbent articles containing additives TST, TMT1A, MPST TRPA1 781/4885ALDH1A1 2270/4885TDP1 1605/4885
US-20030158156-A1 Methods for inhibiting the production of TSST-1 TST, TSSK1B, DNTT TRPA1 4245/4885ALDH1A1 3495/4885TDP1 1529/4885
US-20030165559-A1 Non-absorbent articles containing additives CNOT1, DCUN1D1, CNDP2 TRPA1 520/4885ALDH1A1 3289/4885TDP1 1263/4885
US-20030096877-A1 Inhibition of exoprotein production in non-absorbent articles using isoprenoid compositions FNTA, FNTB, GGPS1 TRPA1 4579/4885ALDH1A1 4719/4885TDP1 4445/4885
US-20050070604-A1 Inhibition of exoprotein production using isoprenoid compositions EXOC1, EXOC4, EXOC3 TRPA1 4828/4885ALDH1A1 4800/4885TDP1 4192/4885
US-20030157148-A1 Methods for inhibiting the production of TSST-1 TST, TMT1A, MPST TRPA1 3097/4885ALDH1A1 3534/4885TDP1 1501/4885
US-20030157149-A1 Menstrual tampons comprising cerulenin, triclosan, or hexachlorophene to inhibit production of toxic shock syndrome toxins by gram-positive bacteria TPSAB1, TPT1, TST TRPA1 134/4885ALDH1A1 3909/4885TDP1 1758/4885
US-10590152-B2 Pinene-based flame retardant compounds PFAS, PNN, PFN1 TRPA1 555/4885ALDH1A1 2048/4885TDP1 691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.