Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915922 | 0.86 | MEN1 (0.40) | ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL24915920 | 0.83 | L3MBTL1 (0.37) | TLR8TLR7HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24916059 | 0.77 | POLB (0.41) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24916001 | 0.73 | HTT (0.44) | HTTRAD52SMN1; SMN2UHRF1ALDH1A1 | |
| SCHEMBL29923768 | 0.71 | EGLN1 (0.52) | HTTRAD52SMN1; SMN2UHRF1ALDH1A1 | |
| SCHEMBL24915997 | 0.70 | GPR52 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL24916013 | 0.70 | MAP4K4 (0.40) | TLR8TLR7 | |
| SCHEMBL9607575 | 0.67 | ALDH1A1 (0.43) | TLR9TLR8TLR7HTTSMN1; SMN2 | |
| SCHEMBL7033962 | 0.67 | AOX1 (0.69) | HTTRAD52SMN1; SMN2UHRF1ALDH1A1 | |
| SCHEMBL24916053 | 0.67 | DHFR (0.43) | KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | TLR9 4379/4885TLR8 4298/4885TLR7 4346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.