SCHEMBL2493585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2464039	0.91	ADORA3 (0.38)	ADORA3CTSGKLK7KLK14KLK5
	SCHEMBL2584501	0.88	CHRM1 (0.38)	ADORA3CHRM1ROCK2TSHRMAPT
	SCHEMBL2581675	0.88	ADORA3 (0.36)	ADORA3CTSGKLK7KLK14KLK5
	SCHEMBL2494743	0.86	CHRM1 (0.34)	CHRM1AR
	SCHEMBL14479040	0.84	PDE4D (0.38)	ADORA3CHRM1ROCK2CRHR1TAS1R3
	SCHEMBL15472254	0.82	PDE4D (0.36)	ADORA3CHRM1TSHRMAPTMAPK1
	SCHEMBL15472253	0.81	CHRM1 (0.33)	CHRM1ROCK2BRD4
	SCHEMBL14479035	0.81	PDE4D (0.34)	ADORA3CHRM1CRHR1GABRG2GABRB3
	SCHEMBL2462952	0.81	CHRM1 (0.37)	CHRM1KDM4EHSD17B10
	SCHEMBL2488754	0.80	CHRM1 (0.37)	CHRM1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.