SCHEMBL24974367

SCHEMBL24974367

CCCNC(=O)CCS(=O)(=O)N1CCC(N2CC(=O)N(c3ccccc3)C2=O)CC1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
KMT2A Q03164 3/20 0.39
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
THRB P10828 1/20 0.38
GAA P10253 1/20 0.38
MEN1 O00255 2/20 0.38
UBE2M P61081 1/20 0.37
DCUN1D1 Q96GG9 1/20 0.37
CYP3A4 P08684 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21150757 0.85 ALDH1A1 (0.39) SMN1; SMN2KMT2ACYP1A2CYP2C9MEN1
SCHEMBL21150756 0.80 GPR119 (0.37) KMT2AMEN1KDM4E
SCHEMBL21122066 0.76 PKM (0.49)
SCHEMBL24974603 0.75 NAMPT (0.43) KMT2ACYP2C19CYP2C9MEN1UBE2M
SCHEMBL24974538 0.74 SLC6A9 (0.44) THRB
SCHEMBL21150805 0.70 YAP1 (0.46) SMN1; SMN2KMT2ACYP2C19CYP2C9MEN1
SCHEMBL24974751 0.66 ALDH1A1 (0.38) SMN1; SMN2KMT2ACYP2C19CYP1A2CYP2C9
SCHEMBL29590229 0.66 GRM4 (0.48) SMN1; SMN2KMT2AGAAMEN1
SCHEMBL21150798 0.66 GPR119 (0.57) THRBKDM4E
SCHEMBL24974777 0.65 KMT2A (0.47) KMT2ACYP2C19CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B SMN1; SMN2 3020/4885KMT2A 499/4885CYP2C19 3692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.