SCHEMBL2498455

SCHEMBL2498455

O=S1(=O)c2ccccc2N(c2ccccc2)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.53
TP53 P04637 2/20 0.44
GPR3 P46089 1/20 0.44
LMNA P02545 4/20 0.43
MAPT P10636 2/20 0.43
THRB P10828 1/20 0.43
POLB P06746 1/20 0.43
GAA P10253 2/20 0.42
CES2 O00748 1/20 0.42
ALDH1A1 P00352 1/20 0.42
BCHE P06276 1/20 0.42
CES1 P23141 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MGLL Q99685 1/20 0.41
HPGD P15428 1/20 0.41
NOX1 Q9Y5S8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12190900 0.93 RXFP1 (0.50) RXFP1TP53GPR3LMNAMAPT
SCHEMBL21666686 0.91 RXFP1 (0.46) RXFP1TP53GPR3LMNAMAPT
SCHEMBL12190905 0.88 RXFP1 (0.46) RXFP1TP53GPR3LMNAMAPT
SCHEMBL12190854 0.88 RXFP1 (0.46) RXFP1TP53GPR3LMNAMAPT
SCHEMBL12190855 0.87 RXFP1 (0.48) RXFP1TP53GPR3LMNAMAPT
SCHEMBL20391572 0.84 RXFP1 (0.43) RXFP1TP53GPR3LMNAMAPT
SCHEMBL20275927 0.84 LMNA (0.58) RXFP1TP53GPR3LMNAMAPT
SCHEMBL21666738 0.84 RXFP1 (0.43) RXFP1TP53GPR3LMNAMAPT
SCHEMBL2497311 0.84 RXFP1 (0.43) RXFP1TP53GPR3LMNAMAPT
SCHEMBL12349305 0.84 RXFP1 (0.44) RXFP1TP53GPR3LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10577537-B2 Light emitting material, manufacture method thereof and organic light emitting diode using the light emitting material TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2020-03-03 US disclosed
US-20190177611-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2019-06-13 US disclosed
US-10280365-B2 Light emitting material, manufacture method thereof and organic light emitting diode using the light emitting material SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2019-05-07 US disclosed
US-10208013-B2 Light emitting material, manufacture method thereof and organic light emitting diode using the light emitting material SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2019-02-19 US disclosed
US-20180201832-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-07-19 US disclosed
US-20180205025-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-07-19 US disclosed
US-20180170901-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-06-21 US disclosed
US-20180170894-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-06-21 US disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
US-8029919-B2 Phenothiazines, S-oxides, and S,S-dioxides as well as phenoxazines as emitters for OLEDs BASF AKTIENGESELLSCHAFT (DE) 2011-10-04 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10280365-B2 Light emitting material, manufacture method thereof and organic light emitting diode using the light emitting material TPMT, UBE2M, UFM1 RXFP1 4867/4885TP53 3087/4885GPR3 4661/4885
US-10208013-B2 Light emitting material, manufacture method thereof and organic light emitting diode using the light emitting material TPMT, UFM1, UBE2M RXFP1 4854/4885TP53 3793/4885GPR3 4568/4885
US-20190177611-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL TPMT, UFM1, AUP1 RXFP1 4866/4885TP53 3530/4885GPR3 4709/4885
US-20180205025-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL TPMT, UFM1, UBE2M RXFP1 4854/4885TP53 3793/4885GPR3 4568/4885
US-20180170894-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL UBE2M, UFM1, UFL1 RXFP1 4845/4885TP53 3086/4885GPR3 4271/4885
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds PPOX, SMOX, SORD RXFP1 4687/4885TP53 3350/4885GPR3 1539/4885
US-10577537-B2 Light emitting material, manufacture method thereof and organic light emitting diode using the light emitting material TPMT, UFM1, AUP1 RXFP1 4866/4885TP53 3530/4885GPR3 4709/4885
US-20180170901-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL TPMT, UFM1, UBE2M RXFP1 4854/4885TP53 3793/4885GPR3 4568/4885
US-20180201832-A1 LIGHT EMITTING MATERIAL, MANUFACTURE METHOD THEREOF AND ORGANIC LIGHT EMITTING DIODE USING THE LIGHT EMITTING MATERIAL TPMT, UFM1, UBE2M RXFP1 4864/4885TP53 3419/4885GPR3 4600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.