SCHEMBL250617

SCHEMBL250617

CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(c1ccccc1)c1ccccc1)C2

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.77
CYP2D6 P10635 4/20 0.77
CYP2C9 P11712 2/20 0.77
HSD17B10 Q99714 2/20 0.77
CHRM2 P08172 8/20 0.75
CHRM5 P08912 8/20 0.75
CHRM1 P11229 8/20 0.75
CHRM3 P20309 8/20 0.75
CHRM4 P08173 7/20 0.75
BLM P54132 4/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
TDP1 Q9NUW8 1/20 0.75
HTR2C P28335 2/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
KDM4E B2RXH2 1/20 0.71
POLB P06746 1/20 0.71
ADRA2C P18825 1/20 0.71
ADRA1A P35348 1/20 0.71
HRH1 P35367 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8872524 1.00 LMNA (0.77) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL22394823 0.87 CYP2D6 (0.76) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL22394824 0.87 CYP2D6 (0.76) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL9653008 0.87 LMNA (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL23494999 0.87 CYP2D6 (0.76) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL23495043 0.87 LMNA (0.75) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL23494998 0.87 CYP2D6 (0.76) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL23495044 0.87 LMNA (0.75) LMNACYP2D6CYP2C9HSD17B10CHRM2
SCHEMBL22394825 0.87 CYP2D6 (0.76) LMNACYP2D6CYP2C9HSD17B10CHRM2
Homatropine SCHEMBL23468168 0.87 LMNA (1.00) LMNACYP2D6CYP2C9HSD17B10CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors REGENERON PHARMA (US) 2026-04-09 US disclosed
US-12472241-B2 Treatment of respiratory disorders with arachidonate 15-lipoxygenase (ALOX15) inhibitors REGENERON PHARMACEUTICALS, INC. (US) 2025-11-18 US disclosed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 US disclosed
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FIRST WAVE BIO, INC. (US) 2023-10-24 US disclosed
US-11744812-B2 Methods of treatment FIRST WAVE BIO, INC. (US) 2023-09-05 US disclosed
US-20230201143-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2023-06-29 US disclosed
WO-2023118074-A1 COMPRESSIBLE AND FREE FLOWING CO-PROCESSED MESOPOROUS SILICA UNIVERZA V LJUBLJANI (SI) 2023-06-29 WO disclosed
US-20230190684-A1 METHODS OF TREATING COVID-19 WITH A NICLOSAMIDE COMPOUND FIRST WAVE BIO, INC. 2023-06-22 US disclosed
US-5661142-A ADMINISTERING DEXAMETHASONE, METOCLOPRAMIDE AND AN ANTIHISTAMINE OT AN ANTICHOLINERGIC AGENT ODYSSEY PHARMACEUTICALS, LLC 1997-08-26 US disclosed
US-5656286-A BLEND OF TWO POLYMERS; PRESSURE SENSITIVE ADHESIVE NOVEN PHARMACEUTICALS, INC. (US) 1997-08-12 US disclosed
US-5614629-A QUATERNARIUM COMPOUNDS FOR TEMPLATES MOBIL OIL CORPORATION (US) 1997-03-25 US disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
WO-1996040086-A2 COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 US disclosed
EP-0195498-A2 Tropane derivatives, their synthesis and their use MOBIL OIL CORPORATION (US) 1986-09-24 EP disclosed
US-4004013-A 2,4,6,8-Tetra-methyl-2,4,6,8-tetraazabicyclo-[3.3.0]-octanedi-3,7-one in treating psychic disorders NOVIKOV SERGEI SERGEEVICH 1977-01-18 US disclosed
US-3966742-A Tetra-N-alkyl derivatives of bicyclic ureas and method of their production NOVIKOV SERGEI SERGEEVICH 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 LMNA 3221/4885CYP2D6 953/4885CYP2C9 957/4885
US-20230190684-A1 METHODS OF TREATING COVID-19 WITH A NICLOSAMIDE COMPOUND ACE2, ACE, MME LMNA 3278/4885CYP2D6 179/4885CYP2C9 14/4885
US-11744812-B2 Methods of treatment ACE2, ACE, SI LMNA 2771/4885CYP2D6 239/4885CYP2C9 27/4885
US-20230201143-A1 METHODS OF TREATMENT ACE2, ACE, SI LMNA 2903/4885CYP2D6 259/4885CYP2C9 35/4885
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors ALOX15, ALOX15B, ALOX5 LMNA 1753/4885CYP2D6 217/4885CYP2C9 603/4885
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FH, CS, ECHS1 LMNA 3341/4885CYP2D6 865/4885CYP2C9 891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.