Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502725 | 0.72 | RAB9A (0.44) | L3MBTL1TSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL25265174 | 0.68 | L3MBTL1 (0.33) | L3MBTL1TSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL30405281 | 0.67 | FAAH (0.42) | L3MBTL1TSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL5491470 | 0.64 | ATM (0.54) | L3MBTL1TSHRALDH1A1NPSR1RAB9A | |
| SCHEMBL2658161 | 0.64 | L3MBTL1 (0.41) | L3MBTL1TSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL23143751 | 0.64 | L3MBTL1 (0.46) | L3MBTL1TSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL2651522 | 0.64 | L3MBTL1 (0.46) | L3MBTL1TSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL40274 | 0.64 | ALDH1A1 (0.61) | L3MBTL1TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4148707 | 0.64 | ALDH1A1 (0.47) | TSHRALDH1A1NPSR1SMN1; SMN2RAB9A | |
| SCHEMBL28667866 | 0.64 | ACHE (0.47) | TSHRALDH1A1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |