Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28941733 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL3823293 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL11474038 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL4344879 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL11472543 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL23037447 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL2539498 | 0.97 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL23534093 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL23534085 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL23534083 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423786-B | Compounds which can be crosslinked by hydrosilylation | 瓦克化学股份公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3911708-B1 | COMPOUNDS THAT CAN BE CROSSLINKED BY WAY OF HYDROSILYLATION REACTION | WACKER CHEMIE AG (DE) | 2022-06-15 | — | — | EP | disclosed |
| CN-113423786-A | Compounds which can be crosslinked by hydrosilylation | 瓦克化学股份公司 | 2021-09-21 | — | — | CN | disclosed |
| US-9018413-B2 | Method for the production of alkylphosphonic acids, esters, and salts by oxidizing alkylphosphonous acids, and use thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-04-28 | — | — | US | disclosed |
| US-20110251314-A1 | Method for the Production of Alkylphosphonic Acids, Esters, and Salts by Oxidizing Alkylphosphonous Acids, and Use Thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-10-13 | — | — | US | disclosed |
| EP-2100916-A1 | Acid scavenger compositions | Clariant International Ltd. (CH) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251314-A1 | Method for the Production of Alkylphosphonic Acids, Esters, and Salts by Oxidizing Alkylphosphonous Acids, and Use Thereof | ACSL3, SCO2, HAO2 | LPAR3 128/4885LPAR2 139/4885TRPM8 2763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.