SCHEMBL2521077

SCHEMBL2521077

O=C(O)CCCCc1ccc(C=Cc2cc(CCCCC(=O)O)cc(CCCCC(=O)O)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.54
▸ RXFP1 Q9HBX9 1/20 0.54
▸ ALB P02768 1/20 0.50
▸ HDAC2 Q92769 2/20 0.49
▸ HDAC3 O15379 1/20 0.49
▸ MAPK1 P28482 1/20 0.49
▸ ADRA1A P35348 1/20 0.49
▸ HDAC4 P56524 1/20 0.49
▸ SLC6A3 Q01959 1/20 0.49
▸ HDAC1 Q13547 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ HDAC7 Q8WUI4 1/20 0.49
▸ HDAC10 Q969S8 1/20 0.49
▸ HDAC11 Q96DB2 1/20 0.49
▸ HDAC8 Q9BY41 1/20 0.49
▸ HDAC6 Q9UBN7 1/20 0.49
▸ HDAC9 Q9UKV0 1/20 0.49
▸ HDAC5 Q9UQL6 1/20 0.49
▸ PPARA Q07869 2/20 0.48
▸ HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2516535 0.91 ALB (0.59) MAPTRXFP1ALBHDAC2HDAC3
SCHEMBL2517612 0.91 ALB (0.55) MAPTRXFP1ALBSMN1; SMN2HDAC6
SCHEMBL2521980 0.88 ALB (0.66) MAPTRXFP1ALBHDAC2HDAC3
SCHEMBL2515313 0.85 ALB (0.59) MAPTRXFP1ALBSMN1; SMN2HDAC6
SCHEMBL7065645 0.80 MAPT (0.79) MAPTRXFP1HDAC2HDAC3MAPK1
SCHEMBL23174459 0.80 MAPT (0.61) MAPTRXFP1HDAC2HDAC3MAPK1
SCHEMBL9671779 0.78 MAPT (0.83) MAPTRXFP1HDAC2HDAC3MAPK1
SCHEMBL3814880 0.78 MAPT (0.83) MAPTRXFP1HDAC2HDAC3MAPK1
SCHEMBL10897221 0.78 MAPT (0.65) MAPTRXFP1HDAC2HDAC3MAPK1
SCHEMBL3196140 0.78 MAPT (0.59) MAPTRXFP1HDAC2HDAC3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 — — US claimed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 — — US claimed
US-9861564-B2 Valeric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT, LLC (US) 2018-01-09 — — US disclosed
US-9782335-B2 Malic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2017-10-10 — — US disclosed
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-10-20 — — US disclosed
EP-2445511-B1 SKIN REPAIR COMPOSITIONS COMPRISING CIRCADIAN GENE ACTIVATORS AND A SYNERGISTIC COMBINATION OF SIRT1 GENE ACTIVATORS ELC MAN LLC (US) 2016-09-07 — — EP disclosed
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-08-11 — — US disclosed
US-9358194-B2 Succinic acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2016-06-07 — — US disclosed
US-9295621-B2 Emulsion cosmetic compositions containing resveratrol derivatives and silicone surfactant ELC MANAGEMENT LLC (US) 2016-03-29 — — US disclosed
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions ELC MAN LLC (US) 2016-02-11 — — US disclosed
US-9180316-B2 Butyric acid esters of resveratrol and cosmetic compositions ELC MANAGEMENT LLC (US) 2015-11-10 — — US disclosed
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2011-10-13 — — US disclosed
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions MAES DANIEL H 2010-08-26 — — US disclosed
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin MAES DANIEL H 2010-04-01 — — US disclosed
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN ELC MANAGEMENT LLC 2009-02-19 — — US disclosed
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 — — US disclosed
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant ELC MANAGEMENT LLC 2009-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090035243-A1 Anhydrous Cosmetic Compositions Containing Resveratrol Derivatives RB1, SIRT1, EP300 MAPT 235/4885RXFP1 2283/4885ALB 672/4885
US-20090035242-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Linear Or Branched Silicone SQLE, SMURF1, PIK3R1 MAPT 1814/4885RXFP1 681/4885ALB 1378/4885
US-20100216879-A1 Resveratrol Ferulate Compounds And Compositions FER, FOLR1, FOLR2 MAPT 2001/4885RXFP1 289/4885ALB 298/4885
US-20090047309-A1 COSMETIC METHODS AND COMPOSITIONS FOR REPAIRING HUMAN SKIN CUTA, ERCC1, OGG1 MAPT 2177/4885RXFP1 922/4885ALB 3897/4885
US-20110250251-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 MAPT 2177/4885RXFP1 922/4885ALB 3897/4885
US-20160303016-A1 Valeric Acid Esters Of Resveratrol And Cosmetic Compositions CUTA, SUV39H1, RARA MAPT 1397/4885RXFP1 2686/4885ALB 1869/4885
US-20090035237-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And Silicone Surfactant SMURF1, CUTA, SMURF2 MAPT 2543/4885RXFP1 1003/4885ALB 1597/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA MAPT 1386/4885RXFP1 888/4885ALB 2358/4885
US-20090035240-A1 Aqueous Based Cosmetic Compositions Containing Resveratrol Derivatives And An Aqueous Phase Structuring Agent SMARCC1, RARG, RARA MAPT 899/4885RXFP1 1110/4885ALB 2833/4885
US-20100080845-A1 Cosmetic Methods And Compositions For Repairing Human Skin CUTA, ERCC1, OGG1 MAPT 2177/4885RXFP1 922/4885ALB 3897/4885
US-20160229791-A1 Malic Acid Esters Of Resveratrol And Cosmetic Compositions ME1, ME2, ME3 MAPT 1409/4885RXFP1 2593/4885ALB 1987/4885
US-20160038389-A1 Succinic Acid Esters Of Resveratrol And Cosmetic Compositions SUCNR1, SIRT1, SUCLA2 MAPT 1534/4885RXFP1 1483/4885ALB 2592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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